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    Emc4 ER membrane protein complex subunit 4 [ Mus musculus (house mouse) ]

    Gene ID: 68032, updated on 23-Jun-2021

    Summary

    Official Symbol
    Emc4provided by MGI
    Official Full Name
    ER membrane protein complex subunit 4provided by MGI
    Primary source
    MGI:MGI:1915282
    See related
    Ensembl:ENSMUSG00000027131
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tmem85; 2610318K02Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 57.7), cortex adult (RPKM 48.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Emc4 in Genome Data Viewer
    Location:
    2; 2 E3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (112193364..112209532, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (112363019..112379476, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (112203176..112208184, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene solute carrier family 12, member 6 Neighboring gene NOP10 ribonucleoprotein Neighboring gene predicted gene, 39908 Neighboring gene katanin p80 subunit B like 1 Neighboring gene ER membrane protein complex subunit 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to membrane insertase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of EMC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of EMC complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ER membrane protein complex subunit 4
    Names
    transmembrane protein 85

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026519.3NP_080795.1  ER membrane protein complex subunit 4

      See identical proteins and their annotated locations for NP_080795.1

      Status: PROVISIONAL

      Source sequence(s)
      AL683897
      Consensus CDS
      CCDS16553.1
      UniProtKB/Swiss-Prot
      Q9CZX9
      Related
      ENSMUSP00000028551.4, ENSMUST00000028551.4
      Conserved Domains (1) summary
      pfam06417
      Location:56170
      DUF1077; Protein of unknown function (DUF1077)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      112193364..112209532 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252000.2XP_030107860.1  ER membrane protein complex subunit 4 isoform X1

      Conserved Domains (1) summary
      pfam06417
      Location:56170
      DUF1077; Protein of unknown function (DUF1077)
    2. XM_030251999.2XP_030107859.1  ER membrane protein complex subunit 4 isoform X1

      Conserved Domains (1) summary
      pfam06417
      Location:56170
      DUF1077; Protein of unknown function (DUF1077)
    3. XM_036162512.1XP_036018405.1  ER membrane protein complex subunit 4 isoform X2

      Conserved Domains (1) summary
      pfam06417
      Location:189
      DUF1077; Protein of unknown function (DUF1077)
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