Format

Send to:

Choose Destination
    • Showing Current items.

    Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 [ Mus musculus (house mouse) ]

    Gene ID: 67972, updated on 5-Mar-2019

    Summary

    Official Symbol
    Atp2b1provided by MGI
    Official Full Name
    ATPase, Ca++ transporting, plasma membrane 1provided by MGI
    Primary source
    MGI:MGI:104653
    See related
    Ensembl:ENSMUSG00000019943
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pmca1; 2810442I22Rik; E130111D10Rik
    Expression
    Broad expression in frontal lobe adult (RPKM 30.2), cortex adult (RPKM 27.6) and 21 other tissues See more
    Orthologs

    Genomic context

    See Atp2b1 in Genome Data Viewer
    Location:
    10; 10 C3
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (98914359..99026143)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (98377786..98488777)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40750 Neighboring gene predicted gene, 34346 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 4 Neighboring gene POC1 centriolar protein B Neighboring gene predicted gene, 34574

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    PDZ domain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    PDZ domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    calcium ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    calcium-transporting ATPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    calcium ion export ISO
    Inferred from Sequence Orthology
    more info
     
    calcium ion export across plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    calcium ion transport TAS
    Traceable Author Statement
    more info
    PubMed 
    cellular calcium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cytosolic calcium ion concentration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    GABA-ergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    apical part of cell ISO
    Inferred from Sequence Orthology
    more info
     
    apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite membrane ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic spine membrane ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    integral component of presynaptic active zone membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane raft ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    plasma membrane calcium-transporting ATPase 1
    Names
    plasma membrane calcium ATPase
    plasma membrane calcium pump
    NP_080758.1
    XP_006514078.1
    XP_011241850.1
    XP_011241851.1
    XP_017169560.1
    XP_017169561.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359506.1NP_001346435.1  plasma membrane calcium-transporting ATPase 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC153906, AC160410, AI892140, AK133920, BI732378, BQ176881, CF750345, CJ128577, CJ321142, CK393435, CK624413, CN691756, CV559947
      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031178
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    2. NM_001359507.1NP_001346436.1  plasma membrane calcium-transporting ATPase 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC153906, AC160410, AI892140, AK133920, BI732378, BQ176881, CF750345, CJ321142, CK393435, CK624413, CN691756, CV559947
      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031142
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    3. NM_001359508.1NP_001346437.1  plasma membrane calcium-transporting ATPase 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC153906, AC160410, AI892140, AK133920, BI732378, BQ176881, CF750345, CJ128577, CJ321142, CK393435, CK624413, CN691756, CV559947
      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031142
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    4. NM_001359509.1NP_001346438.1  plasma membrane calcium-transporting ATPase 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC153906, AC160410, AI892140, AK133920, BI732378, BQ176881, CF750345, CJ128577, CJ321142, CK393435, CK624413, CN691756, CV559947
      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031142
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    5. NM_026482.2NP_080758.1  plasma membrane calcium-transporting ATPase 1 isoform 2

      See identical proteins and their annotated locations for NP_080758.1

      Status: VALIDATED

      Source sequence(s)
      AC153906, AC160410, AI892140, AK133920, BC030901, CJ321142
      Consensus CDS
      CCDS24145.1
      UniProtKB/Swiss-Prot
      G5E829
      Related
      ENSMUSP00000020107.7, ENSMUST00000020107.7
      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031149
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      98914359..99026143
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314072.1XP_017169561.1  plasma membrane calcium-transporting ATPase 1 isoform X4

      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031142
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    2. XM_006514015.3XP_006514078.1  plasma membrane calcium-transporting ATPase 1 isoform X1

      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031178
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    3. XM_011243549.2XP_011241851.1  plasma membrane calcium-transporting ATPase 1 isoform X2

      See identical proteins and their annotated locations for XP_011241851.1

      UniProtKB/Swiss-Prot
      G5E829
      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031149
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    4. XM_011243548.2XP_011241850.1  plasma membrane calcium-transporting ATPase 1 isoform X1

      See identical proteins and their annotated locations for XP_011241850.1

      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031178
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    5. XM_017314071.1XP_017169560.1  plasma membrane calcium-transporting ATPase 1 isoform X3

      Conserved Domains (2) summary
      TIGR01517
      Location:151064
      ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
      pfam12424
      Location:11031142
      ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal

    RNA

    1. XR_001779589.1 RNA Sequence

    2. XR_001779588.1 RNA Sequence

    3. XR_001779587.1 RNA Sequence

    Support Center