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    Sugt1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 67955, updated on 22-Aug-2021

    Summary

    Official Symbol
    Sugt1provided by MGI
    Official Full Name
    SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1915205
    See related
    Ensembl:ENSMUSG00000022024
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SGT; SGT1; 2410174K12Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 23.7), placenta adult (RPKM 20.6) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Sugt1 in Genome Data Viewer
    Location:
    14; 14 D3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (79825100..79868237)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (79587660..79630797)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (79987498..80029562)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA glutamic acid 4 (anticodon TTC) Neighboring gene claspin homolog pseudogene Neighboring gene E74 like ETS transcription factor 1 Neighboring gene chondromodulin Neighboring gene predicted gene, 41218

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in protein stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of protein stability ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    protein SGT1 homolog
    Names
    suppressor of G2 allele of SKP1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026474.6NP_080750.1  protein SGT1 homolog

      See identical proteins and their annotated locations for NP_080750.1

      Status: VALIDATED

      Source sequence(s)
      AC129216, AK082328, AK141416
      Consensus CDS
      CCDS36988.1
      UniProtKB/Swiss-Prot
      Q9CX34
      Related
      ENSMUSP00000052942.9, ENSMUST00000054908.10
      Conserved Domains (6) summary
      cd06489
      Location:146229
      p23_CS_hSgt1_like; p23_like domain similar to the C-terminal CS (CHORD-SGT1) domain of human (h) Sgt1 and related proteins. hSgt1 is a co-chaperone which has been shown to be elevated in HEp-2 cells as a result of stress conditions such as heat shock. It interacts with the ...
      smart00028
      Location:4578
      TPR; Tetratricopeptide repeats
      PLN03088
      Location:21336
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      sd00006
      Location:4474
      TPR; TPR repeat [structural motif]
      cl22853
      Location:38107
      Motor_domain; Myosin and Kinesin motor domain
      pfam05002
      Location:256336
      SGS; SGS domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      79825100..79868237
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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