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    Nifk nucleolar protein interacting with the FHA domain of MKI67 [ Mus musculus (house mouse) ]

    Gene ID: 67949, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nifkprovided by MGI
    Official Full Name
    nucleolar protein interacting with the FHA domain of MKI67provided by MGI
    Primary source
    MGI:MGI:1915199
    See related
    Ensembl:ENSMUSG00000026377
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mki6; Mki67ip; AI852665; C130020J04Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 22.8), liver E14 (RPKM 16.9) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Nifk in Genome Data Viewer
    Location:
    1; 1 E2.3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (118249573..118261561)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (118321843..118333831)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (120218420..120230408)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53580 Neighboring gene translin Neighboring gene predicted gene 28867 Neighboring gene CLIP associating protein 1 Neighboring gene predicted gene, 26080

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in condensed nuclear chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    MKI67 FHA domain-interacting nucleolar phosphoprotein
    Names
    Mki67 (FHA domain) interacting nucleolar phosphoprotein
    mNIFK
    nucleolar protein interacting with the FHA domain of pKI-67

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026472.4NP_080748.3  MKI67 FHA domain-interacting nucleolar phosphoprotein

      See identical proteins and their annotated locations for NP_080748.3

      Status: VALIDATED

      Source sequence(s)
      BB727432, BC058559, BY289326
      Consensus CDS
      CCDS15222.1
      UniProtKB/Swiss-Prot
      Q91VE6
      Related
      ENSMUSP00000027626.7, ENSMUST00000027626.13
      Conserved Domains (3) summary
      COG0724
      Location:48156
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12307
      Location:48121
      RRM_NIFK_like; RNA recognition motif in nucleolar protein interacting with the FHA domain of pKI-67 (NIFK) and similar proteins
      pfam12196
      Location:251288
      hNIFK_binding; FHA Ki67 binding domain of hNIFK

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      118249573..118261561
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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