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    Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit [ Mus musculus (house mouse) ]

    Gene ID: 67877, updated on 23-Jun-2021

    Summary

    Official Symbol
    Naa20provided by MGI
    Official Full Name
    N(alpha)-acetyltransferase 20, NatB catalytic subunitprovided by MGI
    Primary source
    MGI:MGI:1915127
    See related
    Ensembl:ENSMUSG00000002728
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Na; Nat5; AU041458; D2Ertd186; D2Ertd186e; 1500004D14Rik; 2900026I01Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 9.7), placenta adult (RPKM 9.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Naa20 in Genome Data Viewer
    Location:
    2 G1; 2 71.28 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (145743454..145758345)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (145901539..145916425)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (145728977..145742161)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene Ras and Rab interactor 2 Neighboring gene predicted gene, 54121 Neighboring gene predicted gene, 39954 Neighboring gene TM2 domain containing 1 pseudogene Neighboring gene crooked neck pre-mRNA splicing factor 1 Neighboring gene cilia and flagella associated protein 61 Neighboring gene predicted gene, 34629

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC144325

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptide alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in N-terminal peptidyl-methionine acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of NatB complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 20
    Names
    N-acetyltransferase 5 (ARD1 homolog, S. cerevisiae)
    N-terminal acetyltransferase B complex catalytic subunit NAA20
    N-terminal acetyltransferase B complex catalytic subunit NAT5
    methionine N-acetyltransferase
    natB catalytic subunit
    natB complex subunit NAT5
    NP_001135437.1
    NP_080701.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001141965.1NP_001135437.1  N-alpha-acetyltransferase 20 isoform 1

      See identical proteins and their annotated locations for NP_001135437.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1).
      Source sequence(s)
      AK005143, AK009229, CO802916
      Consensus CDS
      CCDS50735.1
      UniProtKB/Swiss-Prot
      P61600
      UniProtKB/TrEMBL
      Q9DB82
      Related
      ENSMUSP00000105627.2, ENSMUST00000110000.8
      Conserved Domains (1) summary
      COG0456
      Location:1156
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
    2. NM_026425.3NP_080701.1  N-alpha-acetyltransferase 20 isoform 2

      See identical proteins and their annotated locations for NP_080701.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an in-frame alternate splice site in the coding region, compared to variant 1, and encodes a longer protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AK005143, AK009229, CO802916
      Consensus CDS
      CCDS16827.1
      UniProtKB/Swiss-Prot
      P61600
      UniProtKB/TrEMBL
      Q9DB82
      Related
      ENSMUSP00000002805.8, ENSMUST00000002805.14
      Conserved Domains (1) summary
      COG0456
      Location:1166
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      145743454..145758345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_003953700.2 RNA Sequence

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