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    Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit [ Mus musculus (house mouse) ]

    Gene ID: 67877, updated on 5-Aug-2018

    Summary

    Official Symbol
    Naa20provided by MGI
    Official Full Name
    N(alpha)-acetyltransferase 20, NatB catalytic subunitprovided by MGI
    Primary source
    MGI:MGI:1915127
    See related
    Ensembl:ENSMUSG00000002728 Vega:OTTMUSG00000004059
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nat5; AU041458; D2Ertd186e; 1500004D14Rik; 2900026I01Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 9.7), placenta adult (RPKM 9.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Naa20 in Genome Data Viewer
    Location:
    2 G1; 2 71.28 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (145901581..145916425)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (145728977..145742161)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene Ras and Rab interactor 2 Neighboring gene predicted gene, 39954 Neighboring gene TM2 domain containing 1 pseudogene Neighboring gene crooked neck pre-mRNA splicing factor 1 Neighboring gene cilia and flagella associated protein 61

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC144325

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    peptide alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    N-terminal peptidyl-methionine acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    NatB complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 20
    Names
    N-acetyltransferase 5 (ARD1 homolog, S. cerevisiae)
    N-terminal acetyltransferase B complex catalytic subunit NAA20
    N-terminal acetyltransferase B complex catalytic subunit NAT5
    methionine N-acetyltransferase
    natB catalytic subunit
    natB complex subunit NAT5
    NP_001135437.1
    NP_080701.1
    XP_006500152.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001141965.1NP_001135437.1  N-alpha-acetyltransferase 20 isoform 1

      See identical proteins and their annotated locations for NP_001135437.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1).
      Source sequence(s)
      AK005143, AK009229, CO802916
      Consensus CDS
      CCDS50735.1
      UniProtKB/Swiss-Prot
      P61600
      UniProtKB/TrEMBL
      Q9DB82
      Related
      ENSMUSP00000105627.1, OTTMUSP00000004399, ENSMUST00000110000.7, OTTMUST00000009059
      Conserved Domains (1) summary
      COG0456
      Location:1156
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
    2. NM_026425.3NP_080701.1  N-alpha-acetyltransferase 20 isoform 2

      See identical proteins and their annotated locations for NP_080701.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an in-frame alternate splice site in the coding region, compared to variant 1, and encodes a longer protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AK005143, AK009229, CO802916
      Consensus CDS
      CCDS16827.1
      UniProtKB/Swiss-Prot
      P61600
      UniProtKB/TrEMBL
      Q9DB82
      Related
      ENSMUSP00000002805.7, OTTMUSP00000004400, ENSMUST00000002805.13, OTTMUST00000009060
      Conserved Domains (1) summary
      COG0456
      Location:1166
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      145901581..145916425
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500089.3XP_006500152.1  N-alpha-acetyltransferase 20 isoform X1

      Related
      ENSMUSP00000132857.1, OTTMUSP00000049431, ENSMUST00000169732.7, OTTMUST00000090196
      Conserved Domains (2) summary
      COG0456
      Location:1112
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:67108
      Acetyltransf_1; Acetyltransferase (GNAT) family
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