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    Enoph1 enolase-phosphatase 1 [ Mus musculus (house mouse) ]

    Gene ID: 67870, updated on 31-Jan-2019

    Summary

    Official Symbol
    Enoph1provided by MGI
    Official Full Name
    enolase-phosphatase 1provided by MGI
    Primary source
    MGI:MGI:1915120
    See related
    Ensembl:ENSMUSG00000029326
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C81437; BB183658; 2310057D15Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 19.1), adrenal adult (RPKM 18.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Enoph1 in Genome Data Viewer
    Location:
    5; 5 E4
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (100039953..100068925)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (100469013..100497784)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein D Neighboring gene predicted gene, 42127 Neighboring gene heterogeneous nuclear ribonucleoprotein D-like Neighboring gene transmembrane protein 150C, opposite strand Neighboring gene transmembrane protein 150C Neighboring gene predicted gene, 36167

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    acireductone synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acireductone synthase activity ISO
    Inferred from Sequence Orthology
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    L-methionine salvage from methylthioadenosine IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    L-methionine salvage from methylthioadenosine ISO
    Inferred from Sequence Orthology
    more info
     
    cellular amino acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    methionine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    enolase-phosphatase E1
    Names
    2,3-diketo-5-methylthio-1-phosphopentane phosphatase
    MASA homolog
    NP_001156507.1
    NP_080697.2
    XP_006535252.1
    XP_006535253.1
    XP_011247852.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163035.1NP_001156507.1  enolase-phosphatase E1

      See identical proteins and their annotated locations for NP_001156507.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AK079062, AK080714, AK167575, BE995909
      Consensus CDS
      CCDS39183.1
      UniProtKB/Swiss-Prot
      Q8BGB7
      Related
      ENSMUSP00000031268.6, ENSMUST00000031268.7
      Conserved Domains (2) summary
      pfam13419
      Location:13227
      HAD_2; Haloacid dehalogenase-like hydrolase
      cl21460
      Location:10252
      HAD_like; Haloacid Dehalogenase-like Hydrolases
    2. NM_026421.3NP_080697.2  enolase-phosphatase E1

      See identical proteins and their annotated locations for NP_080697.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AK079062, AK167575, BE995909
      Consensus CDS
      CCDS39183.1
      UniProtKB/Swiss-Prot
      Q8BGB7
      Related
      ENSMUSP00000129704.1, ENSMUST00000169390.7
      Conserved Domains (2) summary
      pfam13419
      Location:13227
      HAD_2; Haloacid dehalogenase-like hydrolase
      cl21460
      Location:10252
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    RNA

    1. NR_027990.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice junction at the 3' end of the first exon compared to variant 1, that causes a frameshift. The resulting transcript is a candidate for nonsense-mediated mRNA decay (NMD), and therefore is not thought to be protein-coding.
      Source sequence(s)
      AK079062, AK167575, BE995909, CX235072

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      100039953..100068925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006535190.2XP_006535253.1  enolase-phosphatase E1 isoform X1

      See identical proteins and their annotated locations for XP_006535253.1

      Conserved Domains (2) summary
      pfam13419
      Location:105235
      HAD_2; Haloacid dehalogenase-like hydrolase
      cl21460
      Location:10263
      HAD_like; Haloacid Dehalogenase-like Hydrolases
    2. XM_011249550.2XP_011247852.1  enolase-phosphatase E1 isoform X1

      See identical proteins and their annotated locations for XP_011247852.1

      Conserved Domains (2) summary
      pfam13419
      Location:105235
      HAD_2; Haloacid dehalogenase-like hydrolase
      cl21460
      Location:10263
      HAD_like; Haloacid Dehalogenase-like Hydrolases
    3. XM_006535189.2XP_006535252.1  enolase-phosphatase E1 isoform X1

      See identical proteins and their annotated locations for XP_006535252.1

      Conserved Domains (2) summary
      pfam13419
      Location:105235
      HAD_2; Haloacid dehalogenase-like hydrolase
      cl21460
      Location:10263
      HAD_like; Haloacid Dehalogenase-like Hydrolases
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