Format

Send to:

Choose Destination
    • Showing Current items.

    Slc25a11 solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 [ Mus musculus (house mouse) ]

    Gene ID: 67863, updated on 23-Jun-2021

    Summary

    Official Symbol
    Slc25a11provided by MGI
    Official Full Name
    solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11provided by MGI
    Primary source
    MGI:MGI:1915113
    See related
    Ensembl:ENSMUSG00000014606
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2ox; 2oxoc; 2310022P18Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 208.5), kidney adult (RPKM 85.6) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Slc25a11 in Genome Data Viewer
    Location:
    11 B3; 11 43.21 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (70534845..70538356, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (70644019..70647531, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (70457698..70460495, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12315 Neighboring gene glycoprotein 1b, alpha polypeptide Neighboring gene ring finger protein 167 Neighboring gene profilin 1 Neighboring gene enolase 3, beta muscle Neighboring gene sperm associated antigen 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables alpha-ketoglutarate transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables malate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables oxaloacetate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables succinate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables sulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables thiosulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in malate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in oxaloacetate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in phosphate ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in succinate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in sulfate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in thiosulfate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mitochondrial 2-oxoglutarate/malate carrier protein
    Names
    OGCP
    solute carrier family 25 member 11

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024211.3NP_077173.1  mitochondrial 2-oxoglutarate/malate carrier protein

      See identical proteins and their annotated locations for NP_077173.1

      Status: VALIDATED

      Source sequence(s)
      AI196845, AI931249, AK009487, BY006289
      Consensus CDS
      CCDS24958.1
      UniProtKB/Swiss-Prot
      Q9CR62
      UniProtKB/TrEMBL
      Q5SX53
      Related
      ENSMUSP00000014750.9, ENSMUST00000014750.15
      Conserved Domains (1) summary
      pfam00153
      Location:24102
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      70534845..70538356 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534026.3XP_006534089.1  mitochondrial 2-oxoglutarate/malate carrier protein isoform X1

      See identical proteins and their annotated locations for XP_006534089.1

      Conserved Domains (1) summary
      pfam00153
      Location:186277
      Mito_carr; Mitochondrial carrier protein
    Support Center