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    Ppp6c protein phosphatase 6, catalytic subunit [ Mus musculus (house mouse) ]

    Gene ID: 67857, updated on 5-Aug-2018

    Summary

    Official Symbol
    Ppp6cprovided by MGI
    Official Full Name
    protein phosphatase 6, catalytic subunitprovided by MGI
    Primary source
    MGI:MGI:1915107
    See related
    Ensembl:ENSMUSG00000026753 Vega:OTTMUSG00000012451
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pp6C; 2310003C10Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 11.6), bladder adult (RPKM 11.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ppp6c in Genome Data Viewer
    Location:
    2; 2 B
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (39194369..39226338, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (39052318..39081858, complement)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene suppressor of cancer cell invasion Neighboring gene developmental pluripotency associated 4 pseudogene Neighboring gene mitochondrial ribosomal protein L40 pseudogene Neighboring gene vomeronasal 2, receptor, pseudogene 2 Neighboring gene NEDD4-binding protein 1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    protein dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein phosphatase 6 catalytic subunit
    NP_077171.1
    XP_006498319.1
    XP_017174716.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024209.3NP_077171.1  serine/threonine-protein phosphatase 6 catalytic subunit

      See identical proteins and their annotated locations for NP_077171.1

      Status: VALIDATED

      Source sequence(s)
      AK002764, AK009104, BE634938, BY197919, CD546325
      Consensus CDS
      CCDS16017.1
      UniProtKB/Swiss-Prot
      Q9CQR6
      Related
      ENSMUSP00000028087.3, OTTMUSP00000013324, ENSMUST00000028087.5
      Conserved Domains (1) summary
      cd07415
      Location:5289
      MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      39194369..39226338 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498256.3XP_006498319.1  serine/threonine-protein phosphatase 6 catalytic subunit isoform X1

      See identical proteins and their annotated locations for XP_006498319.1

      Conserved Domains (1) summary
      cl13995
      Location:1211
      MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain
    2. XM_017319227.1XP_017174716.1  serine/threonine-protein phosphatase 6 catalytic subunit isoform X2

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