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    Cdca5 cell division cycle associated 5 [ Mus musculus (house mouse) ]

    Gene ID: 67849, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cdca5provided by MGI
    Official Full Name
    cell division cycle associated 5provided by MGI
    Primary source
    MGI:MGI:1915099
    See related
    Ensembl:ENSMUSG00000024791 AllianceGenome:MGI:1915099
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610036L13Rik
    Summary
    Involved in mitotic cell cycle and mitotic sister chromatid cohesion. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human CDCA5 (cell division cycle associated 5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in liver E14 (RPKM 15.9), liver E14.5 (RPKM 14.6) and 16 other tissues See more
    Orthologs
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    Genomic context

    See Cdca5 in Genome Data Viewer
    Location:
    19 A; 19 4.34 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6135127..6141803)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (6085097..6091773)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene transmembrane 7 superfamily member 2 Neighboring gene VPS51 GARP complex subunit Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:6077181-6077364 Neighboring gene transmembrane protein 262 Neighboring gene STARR-positive B cell enhancer ABC_E3238 Neighboring gene STARR-positive B cell enhancer ABC_E4262 Neighboring gene zinc finger like protein 1 Neighboring gene predicted gene 550 Neighboring gene N-acetylated alpha-linked acidic dipeptidase-like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in double-strand break repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in double-strand break repair ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in double-strand break repair ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitotic cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic chromosome condensation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic chromosome condensation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitotic metaphase chromosome alignment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitotic metaphase chromosome alignment ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic metaphase chromosome alignment ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitotic sister chromatid cohesion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in mitotic sister chromatid cohesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of exit from mitosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of exit from mitosis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of exit from mitosis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    sororin
    Names
    cell division cycle-associated protein 5
    sororin p35

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026410.3NP_080686.1  sororin

      See identical proteins and their annotated locations for NP_080686.1

      Status: PROVISIONAL

      Source sequence(s)
      AC131692
      Consensus CDS
      CCDS29493.1
      UniProtKB/Swiss-Prot
      Q78HI6, Q9CPY3
      Related
      ENSMUSP00000025704.3, ENSMUST00000025704.3
      Conserved Domains (1) summary
      pfam09666
      Location:88223
      Sororin; Sororin protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      6135127..6141803
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)