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    Rnf115 ring finger protein 115 [ Mus musculus (house mouse) ]

    Gene ID: 67845, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rnf115provided by MGI
    Official Full Name
    ring finger protein 115provided by MGI
    Primary source
    MGI:MGI:1915095
    See related
    Ensembl:ENSMUSG00000028098
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rab; Zfp36; Zfp364; AU042696; 2610028E05Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 14.4), CNS E14 (RPKM 14.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rnf115 in Genome Data Viewer
    Location:
    3; 3 F2.1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (96634869..96698471)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96727597..96791155)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (96531534..96595078)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene protein inhibitor of activated STAT 3 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 17 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide C Neighboring gene predicted gene, 22581 Neighboring gene CD160 antigen Neighboring gene RIKEN cDNA 4930442L01 gene Neighboring gene PDZ domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF115
    Names
    RING-type E3 ubiquitin transferase RNF115
    Rab7-interacting RING finger protein
    Rabring7
    rabring 7
    zinc finger protein 364
    NP_080682.3
    XP_006502010.2
    XP_030108633.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026406.3NP_080682.3  E3 ubiquitin-protein ligase RNF115

      See identical proteins and their annotated locations for NP_080682.3

      Status: VALIDATED

      Source sequence(s)
      AC112261, AC127297
      Consensus CDS
      CCDS17647.1
      UniProtKB/Swiss-Prot
      Q9D0C1
      Related
      ENSMUSP00000029740.10, ENSMUST00000029740.14
      Conserved Domains (2) summary
      pfam13639
      Location:228270
      zf-RING_2; Ring finger domain
      pfam14369
      Location:1949
      zinc_ribbon_9; zinc-ribbon

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      96634869..96698471
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501947.5XP_006502010.2  E3 ubiquitin-protein ligase RNF115 isoform X1

      Conserved Domains (1) summary
      cd16800
      Location:188234
      RING-H2_RNF115; RING finger, H2 subclass, found in RING finger protein 115 (RNF115) and similar proteins
    2. XM_030252773.1XP_030108633.1  E3 ubiquitin-protein ligase RNF115 isoform X2

      Conserved Domains (1) summary
      cd16800
      Location:146192
      RING-H2_RNF115; RING finger, H2 subclass, found in RING finger protein 115 (RNF115) and similar proteins
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