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    Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 [ Mus musculus (house mouse) ]

    Gene ID: 67838, updated on 31-Jan-2019

    Summary

    Official Symbol
    Dnajb11provided by MGI
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member B11provided by MGI
    Primary source
    MGI:MGI:1915088
    See related
    Ensembl:ENSMUSG00000004460
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dj9; ERdj3; ERj3p; ABBP-2; AL024055; 1810031F23Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 25.6), liver E14 (RPKM 10.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Dnajb11 in Genome Data Viewer
    Location:
    16; 16 B1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (22857845..22879634)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (22857939..22879707)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 30416 Neighboring gene crystallin, gamma S Neighboring gene TBCC domain containing 1 Neighboring gene predicted gene, 30505 Neighboring gene alpha-2-HS-glycoprotein Neighboring gene predicted gene, 30611

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
    • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    unfolded protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    mRNA modification IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mRNA modification ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of neurogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of neurogenesis IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    negative regulation of neurogenesis ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    protein maturation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum chaperone complex ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dnaJ homolog subfamily B member 11
    Names
    APOBEC1-binding protein 2
    DnaJ (Hsp40) homolog, subfamily B, member 11
    ER-associated Hsp40 co-chaperone
    ER-associated dnaJ protein 3
    ER-resident protein ERdj3
    endoplasmic reticulum DNA J domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190804.1NP_001177733.1  dnaJ homolog subfamily B member 11 precursor

      See identical proteins and their annotated locations for NP_001177733.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AK050500, BY270762, BY617271, BY640220
      Consensus CDS
      CCDS28070.1
      UniProtKB/Swiss-Prot
      Q99KV1
      Related
      ENSMUSP00000004574.7, ENSMUST00000004574.13
      Conserved Domains (1) summary
      COG0484
      Location:22344
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    2. NM_001190805.1NP_001177734.1  dnaJ homolog subfamily B member 11 precursor

      See identical proteins and their annotated locations for NP_001177734.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 3' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AK148511, BY270762, BY617271, BY625840, BY640220, CT027991
      Consensus CDS
      CCDS28070.1
      UniProtKB/Swiss-Prot
      Q99KV1
      Related
      ENSMUSP00000137542.1, ENSMUST00000178320.1
      Conserved Domains (1) summary
      COG0484
      Location:22344
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    3. NM_026400.5NP_080676.3  dnaJ homolog subfamily B member 11 precursor

      See identical proteins and their annotated locations for NP_080676.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AK148511, BY270762
      Consensus CDS
      CCDS28070.1
      UniProtKB/Swiss-Prot
      Q99KV1
      Related
      ENSMUSP00000126828.2, ENSMUST00000166487.9
      Conserved Domains (1) summary
      COG0484
      Location:22344
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      22857845..22879634
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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