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    Snap47 synaptosomal-associated protein, 47 [ Mus musculus (house mouse) ]

    Gene ID: 67826, updated on 5-Sep-2021

    Summary

    Official Symbol
    Snap47provided by MGI
    Official Full Name
    synaptosomal-associated protein, 47provided by MGI
    Primary source
    MGI:MGI:1915076
    See related
    Ensembl:ENSMUSG00000009894
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SNA; SNAP-47; 1110031B06Rik
    Expression
    Broad expression in CNS E18 (RPKM 109.4), cortex adult (RPKM 96.1) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Snap47 in Genome Data Viewer
    Location:
    11; 11 B1.3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (59297967..59340868, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (59407141..59450041, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (59220652..59263458, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene wingless-type MMTV integration site family, member 9A Neighboring gene predicted gene, 51865 Neighboring gene protease, serine 38 Neighboring gene predicted gene 15755 Neighboring gene jumonji domain containing 4 Neighboring gene zinc finger protein 867 Neighboring gene ariadne homolog 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables syntaxin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of BLOC-1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in synaptic vesicle membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    synaptosomal-associated protein 47
    Names
    synaptosomal-associated 47 kDa protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356452.1NP_001343381.1  synaptosomal-associated protein 47 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoforn (1). Variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      AI842642, AK049330, BY104758, CD363532
      Consensus CDS
      CCDS24767.1
      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif
    2. NM_001356454.1NP_001343383.1  synaptosomal-associated protein 47 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate exon in the 3' coding region, leading to a frameshift and an early stop codon, compared to variant 1. It encodes isoform 2, which has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AI842642, AK028053, BY104758
      Conserved Domains (2) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
    3. NM_144521.3NP_653104.1  synaptosomal-associated protein 47 isoform 1

      See identical proteins and their annotated locations for NP_653104.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      AI842642, AK028053, BY104758
      Consensus CDS
      CCDS24767.1
      UniProtKB/Swiss-Prot
      Q8R570
      Related
      ENSMUSP00000010038.4, ENSMUST00000010038.10
      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      59297967..59340868 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534022.5XP_006534085.1  synaptosomal-associated protein 47 isoform X1

      See identical proteins and their annotated locations for XP_006534085.1

      UniProtKB/Swiss-Prot
      Q8R570
      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif
    2. XM_036156921.1XP_036012814.1  synaptosomal-associated protein 47 isoform X2

      Conserved Domains (2) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
    3. XM_036156920.1XP_036012813.1  synaptosomal-associated protein 47 isoform X2

      Conserved Domains (2) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
    4. XM_006534024.5XP_006534087.1  synaptosomal-associated protein 47 isoform X1

      See identical proteins and their annotated locations for XP_006534087.1

      UniProtKB/Swiss-Prot
      Q8R570
      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif
    5. XM_006534023.2XP_006534086.1  synaptosomal-associated protein 47 isoform X1

      See identical proteins and their annotated locations for XP_006534086.1

      UniProtKB/Swiss-Prot
      Q8R570
      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif
    6. XM_036156922.1XP_036012815.1  synaptosomal-associated protein 47 isoform X2

      Conserved Domains (2) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
    7. XM_030246254.2XP_030102114.1  synaptosomal-associated protein 47 isoform X1

      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif
    8. XM_030246252.2XP_030102112.1  synaptosomal-associated protein 47 isoform X1

      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif
    9. XM_030246251.2XP_030102111.1  synaptosomal-associated protein 47 isoform X1

      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif
    10. XM_030246253.2XP_030102113.1  synaptosomal-associated protein 47 isoform X1

      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif
    11. XM_036156919.1XP_036012812.1  synaptosomal-associated protein 47 isoform X1

      Conserved Domains (3) summary
      cd15888
      Location:106170
      SNARE_SNAP47N; N-terminal SNARE motif of SNAP47
      cl17171
      Location:298
      PH-like; Pleckstrin homology-like domain
      cl22856
      Location:353411
      SNARE; SNARE motif
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