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    Ilf2 interleukin enhancer binding factor 2 [ Mus musculus (house mouse) ]

    Gene ID: 67781, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ilf2provided by MGI
    Official Full Name
    interleukin enhancer binding factor 2provided by MGI
    Primary source
    MGI:MGI:1915031
    See related
    Ensembl:ENSMUSG00000001016 AllianceGenome:MGI:1915031
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tex261; Tex267; TEG-267; 6230405A16Rik
    Summary
    Predicted to enable DNA binding activity and double-stranded RNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Located in nucleolus. Is expressed in several structures, including brain; early conceptus; ganglia; gonad; and incisor. Orthologous to human ILF2 (interleukin enhancer binding factor 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 75.1), CNS E14 (RPKM 54.2) and 22 other tissues See more
    Orthologs
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    Genomic context

    See Ilf2 in Genome Data Viewer
    Location:
    3 F1; 3 39.23 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (90383421..90395686)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (90476201..90488379)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene natriuretic peptide receptor 1 Neighboring gene STARR-positive B cell enhancer ABC_E6072 Neighboring gene STARR-positive B cell enhancer ABC_E56 Neighboring gene nuclear encoded tRNA methionine 11 (anticodon CAT) Neighboring gene STARR-positive B cell enhancer ABC_E2084 Neighboring gene SNAP-associated protein Neighboring gene chromatin target of PRMT1 Neighboring gene STARR-positive B cell enhancer ABC_E2085 Neighboring gene STARR-seq mESC enhancer starr_08290 Neighboring gene S100 calcium binding protein A1 Neighboring gene S100 calcium binding protein A13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables double-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables double-stranded RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables double-stranded RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    interleukin enhancer-binding factor 2
    Names
    nuclear factor of activated T-cells 45 kDa
    testis expressed gene 267

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026374.3NP_080650.1  interleukin enhancer-binding factor 2

      See identical proteins and their annotated locations for NP_080650.1

      Status: PROVISIONAL

      Source sequence(s)
      AC160552
      Consensus CDS
      CCDS17530.1
      UniProtKB/Swiss-Prot
      Q3U083, Q5RKG0, Q8CCY9, Q99KS3, Q9CXY6
      UniProtKB/TrEMBL
      Q3UXI9
      Related
      ENSMUSP00000001042.9, ENSMUST00000001042.10
      Conserved Domains (1) summary
      smart00572
      Location:98338
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      90383421..90395686
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163253.1XP_036019146.1  interleukin enhancer-binding factor 2 isoform X1

      Conserved Domains (1) summary
      cl02675
      Location:1182
      DZF; DZF domain