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    Borcs5 BLOC-1 related complex subunit 5 [ Mus musculus (house mouse) ]

    Gene ID: 67774, updated on 23-Jun-2021

    Summary

    Official Symbol
    Borcs5provided by MGI
    Official Full Name
    BLOC-1 related complex subunit 5provided by MGI
    Primary source
    MGI:MGI:1915024
    See related
    Ensembl:ENSMUSG00000042992
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Loh12; AW124643; Loh12cr1; 5830457J20Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 13.0), cortex adult (RPKM 9.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Borcs5 in Genome Data Viewer
    Location:
    6; 6 G1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (134616475..134688147)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (134639512..134711184)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (134589530..134661202)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor-related protein 6 Neighboring gene MANSC domain containing 1 Neighboring gene uncharacterized LOC118567458 Neighboring gene dual specificity phosphatase 16 Neighboring gene predicted gene, 36328 Neighboring gene RIKEN cDNA 1700055D16 gene Neighboring gene predicted gene, 53343

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in lysosome localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in lysosome localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in organelle transport along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in organelle transport along microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of anterograde synaptic vesicle transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of BORC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of BORC complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasmic side of lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasmic side of lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in intrinsic component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in intrinsic component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of plus-end kinesin complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    BLOC-1-related complex subunit 5
    Names
    loss of heterozygosity 12 chromosomal region 1 protein homolog
    loss of heterozygosity, 12, chromosomal region 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170479.1NP_001163950.1  BLOC-1-related complex subunit 5 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AI842379, AK151342, DV652098, DV658678
      Consensus CDS
      CCDS51936.1
      UniProtKB/Swiss-Prot
      Q9D920
      UniProtKB/TrEMBL
      E9Q2W8
      Related
      ENSMUSP00000127413.2, ENSMUST00000166591.8
      Conserved Domains (1) summary
      pfam10158
      Location:62192
      LOH1CR12; Tumour suppressor protein
    2. NM_026371.3NP_080647.2  BLOC-1-related complex subunit 5 isoform 2

      See identical proteins and their annotated locations for NP_080647.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AI842379, AK151342, BY077254
      Consensus CDS
      CCDS20638.1
      UniProtKB/Swiss-Prot
      Q9D920
      Related
      ENSMUSP00000054913.9, ENSMUST00000062755.10
      Conserved Domains (1) summary
      pfam10158
      Location:61191
      LOH1CR12; Tumour suppressor protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      134616475..134688147
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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