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    IARS1 isoleucyl-tRNA synthetase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 677705, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IARS1provided by VGNC
    Official Full Name
    isoleucyl-tRNA synthetase 1provided by VGNC
    Primary source
    VGNC:VGNC:73549
    See related
    Ensembl:ENSMMUG00000004628
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    IARS
    Orthologs
    human mouse all
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    Genomic context

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    See IARS1 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (107311949..107388100, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (42411887..42487351, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene putative UPF0607 protein ENSP00000383144 Neighboring gene Putative serine protease 47 Neighboring gene small nucleolar RNA SNORA84 Neighboring gene nucleolar protein 8 Neighboring gene centromere protein P Neighboring gene osteoglycin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Form deprivation modulates retinal neurogenesis in primate experimental myopia. Tkatchenko AV, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537371, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables isoleucine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in isoleucyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    isoleucine--tRNA ligase, cytoplasmic
    Names
    isoleucine-tRNA synthetase
    isoleucyl-tRNA synthetase, cytoplasmic

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      107311949..107388100 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015117255.2 → XP_014972741.1  isoleucine--tRNA ligase, cytoplasmic

      UniProtKB/TrEMBL
      H9EVI5, H9Z8F3
      Related
      ENSMMUP00000006157.4, ENSMMUT00000006546.4
      Conserved Domains (3) summary
      cd07961
      Location:640 → 833
      Anticodon_Ia_Ile_ABEc; Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases
      cd00818
      Location:39 → 640
      IleRS_core; catalytic core domain of isoleucyl-tRNA synthetases
      PLN02882
      Location:6 → 1071
      PLN02882; aminoacyl-tRNA ligase

    2. XM_015117256.2 → XP_014972742.1  isoleucine--tRNA ligase, cytoplasmic

      UniProtKB/TrEMBL
      H9EVI5, H9Z8F3
      Conserved Domains (3) summary
      cd07961
      Location:640 → 833
      Anticodon_Ia_Ile_ABEc; Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases
      cd00818
      Location:39 → 640
      IleRS_core; catalytic core domain of isoleucyl-tRNA synthetases
      PLN02882
      Location:6 → 1071
      PLN02882; aminoacyl-tRNA ligase
    Nucleotide Protein
    Heading Accession and Version

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