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    Ddx47 DEAD box helicase 47 [ Mus musculus (house mouse) ]

    Gene ID: 67755, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ddx47provided by MGI
    Official Full Name
    DEAD box helicase 47provided by MGI
    Primary source
    MGI:MGI:1915005
    See related
    Ensembl:ENSMUSG00000030204
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C77285; 4930588A18Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 40.9), liver E14 (RPKM 29.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ddx47 in Genome Data Viewer
    Location:
    6; 6 G1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (134988575..135000739)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (135011612..135023776)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (134961630..134973794)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene lncRNA downstream of Cdkn1b Neighboring gene predicted gene, 36428 Neighboring gene apolipoprotein L domain containing 1 Neighboring gene G protein-coupled receptor, family C, group 5, member A Neighboring gene G protein-coupled receptor, family C, group 5, member D

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA splicing ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in extrinsic apoptotic signaling pathway via death domain receptors ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in rRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    probable ATP-dependent RNA helicase DDX47
    Names
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
    DEAD box protein 47
    NP_080636.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026360.3NP_080636.2  probable ATP-dependent RNA helicase DDX47

      See identical proteins and their annotated locations for NP_080636.2

      Status: VALIDATED

      Source sequence(s)
      AK010310, BB682132, BY123864
      Consensus CDS
      CCDS20643.1
      UniProtKB/Swiss-Prot
      Q9CWX9
      UniProtKB/TrEMBL
      Q4VBG1
      Related
      ENSMUSP00000032326.5, ENSMUST00000032326.11
      Conserved Domains (3) summary
      PRK11192
      Location:24446
      PRK11192; ATP-dependent RNA helicase SrmB; Provisional
      cd00079
      Location:237366
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      cd00268
      Location:26227
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      134988575..135000739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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