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    Mrpl18 mitochondrial ribosomal protein L18 [ Mus musculus (house mouse) ]

    Gene ID: 67681, updated on 23-May-2018

    Summary

    Official Symbol
    Mrpl18provided by MGI
    Official Full Name
    mitochondrial ribosomal protein L18provided by MGI
    Primary source
    MGI:MGI:1914931
    See related
    Ensembl:ENSMUSG00000057388 Vega:OTTMUSG00000028084
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C79879; HSPC071; MRP-L18; 1010001C05Rik
    Expression
    Ubiquitous expression in liver E14 (RPKM 33.0), CNS E11.5 (RPKM 30.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Mrpl18 in Genome Data Viewer
    Location:
    17; 17 A1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (12911345..12916478, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (13104221..13108957, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene MAS-related GPR, member H Neighboring gene poly(A)-specific ribonuclease (PARN)-like domain containing 1 Neighboring gene t-complex protein 1 Neighboring gene small nucleolar RNA, H/ACA box 20 Neighboring gene acetyl-Coenzyme A acetyltransferase 3 Neighboring gene t-complex protein 1, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    5S rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    5S rRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    rRNA import into mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    39S ribosomal protein L18, mitochondrial
    Names
    L18mt

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026310.3NP_080586.1  39S ribosomal protein L18, mitochondrial

      See identical proteins and their annotated locations for NP_080586.1

      Status: PROVISIONAL

      Source sequence(s)
      AL589878
      Consensus CDS
      CCDS28396.1
      UniProtKB/Swiss-Prot
      Q9CQL5
      Related
      ENSMUSP00000078123.3, OTTMUSP00000035352, ENSMUST00000079121.3, OTTMUST00000069562
      Conserved Domains (1) summary
      cd00432
      Location:68170
      Ribosomal_L18_L5e; Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      12911345..12916478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523344.1XP_006523407.1  39S ribosomal protein L18, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd00432
      Location:71173
      Ribosomal_L18_L5e; Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA ...
    2. XM_017317617.1XP_017173106.1  39S ribosomal protein L18, mitochondrial isoform X2

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