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    Rpl38 ribosomal protein L38 [ Mus musculus (house mouse) ]

    Gene ID: 67671, updated on 18-Sep-2024

    Summary

    Official Symbol
    Rpl38provided by MGI
    Official Full Name
    ribosomal protein L38provided by MGI
    Primary source
    MGI:MGI:1914921
    See related
    Ensembl:ENSMUSG00000057322 AllianceGenome:MGI:1914921
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ts; Rbt; Tss; 0610025G13Rik
    Summary
    Predicted to be a structural constituent of ribosome. Acts upstream of or within several processes, including 90S preribosome assembly; middle ear morphogenesis; and sensory perception of sound. Part of eukaryotic 80S initiation complex. Is active in synapse. Is expressed in thymus primordium. Used to study otitis media. Orthologous to human RPL38 (ribosomal protein L38). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E11.5 (RPKM 322.3), liver E14 (RPKM 265.4) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rpl38 in Genome Data Viewer
    Location:
    11 79.82 cM; 11 E2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (114558644..114563159)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (114667818..114672333)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53653 Neighboring gene STARR-positive B cell enhancer ABC_E1151 Neighboring gene mitochondrial ribosomal protein S36 pseudogene Neighboring gene tweety family member 2 Neighboring gene dynein axonemal intermediate chain 2 Neighboring gene STARR-positive B cell enhancer mm9_chr11:114606533-114606834

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of eukaryotic 80S initiation complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    large ribosomal subunit protein eL38
    Names
    60S ribosomal protein L38

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001048057.2NP_001041522.1  large ribosomal subunit protein eL38

      See identical proteins and their annotated locations for NP_001041522.1

      Status: VALIDATED

      Source sequence(s)
      AL645484, BC094258, BU921494, CJ042718
      Consensus CDS
      CCDS36365.1
      UniProtKB/Swiss-Prot
      Q9JJI8
      UniProtKB/TrEMBL
      Q52KP0
      Related
      ENSMUSP00000102211.2, ENSMUST00000077915.10
      Conserved Domains (1) summary
      pfam01781
      Location:268
      Ribosomal_L38e; Ribosomal L38e protein family
    2. NM_001048058.2NP_001041523.1  large ribosomal subunit protein eL38

      See identical proteins and their annotated locations for NP_001041523.1

      Status: VALIDATED

      Source sequence(s)
      AL645484, BE448083
      Consensus CDS
      CCDS36365.1
      UniProtKB/Swiss-Prot
      Q9JJI8
      UniProtKB/TrEMBL
      Q52KP0
      Related
      ENSMUSP00000080741.5, ENSMUST00000082092.5
      Conserved Domains (1) summary
      pfam01781
      Location:268
      Ribosomal_L38e; Ribosomal L38e protein family
    3. NM_001362918.1NP_001349847.1  large ribosomal subunit protein eL38

      Status: VALIDATED

      Source sequence(s)
      AL645484, BY687415
      Consensus CDS
      CCDS36365.1
      UniProtKB/Swiss-Prot
      Q9JJI8
      UniProtKB/TrEMBL
      Q52KP0
      Related
      ENSMUSP00000102209.2, ENSMUST00000106599.8
      Conserved Domains (1) summary
      pfam01781
      Location:268
      Ribosomal_L38e; Ribosomal L38e protein family
    4. NM_023372.3NP_075861.1  large ribosomal subunit protein eL38

      See identical proteins and their annotated locations for NP_075861.1

      Status: VALIDATED

      Source sequence(s)
      AL645484, BC094258, BU921494
      Consensus CDS
      CCDS36365.1
      UniProtKB/Swiss-Prot
      Q9JJI8
      UniProtKB/TrEMBL
      Q52KP0
      Related
      ENSMUSP00000102213.4, ENSMUST00000106602.10
      Conserved Domains (1) summary
      pfam01781
      Location:268
      Ribosomal_L38e; Ribosomal L38e protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      114558644..114563159
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314720.1XP_017170209.1  large ribosomal subunit protein eL38 isoform X1

      UniProtKB/Swiss-Prot
      Q9JJI8
      UniProtKB/TrEMBL
      Q52KP0
      Conserved Domains (1) summary
      pfam01781
      Location:268
      Ribosomal_L38e; Ribosomal L38e protein family