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    Anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [ Mus musculus (house mouse) ]

    Gene ID: 67628, updated on 31-Jan-2019

    Summary

    Official Symbol
    Anp32bprovided by MGI
    Official Full Name
    acidic (leucine-rich) nuclear phosphoprotein 32 family, member Bprovided by MGI
    Primary source
    MGI:MGI:1914878
    See related
    Ensembl:ENSMUSG00000028333
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PAL31; Ssp29; PHAPI2a; 2410015B15Rik
    Expression
    Broad expression in liver E14 (RPKM 62.7), liver E14.5 (RPKM 50.7) and 27 other tissues See more
    Orthologs

    Genomic context

    See Anp32b in Genome Data Viewer
    Location:
    4; 4 B1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (46451117..46472532)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (46463989..46485395)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene tRNA methyltransferase O Neighboring gene hemogen Neighboring gene N-acetylneuraminic acid synthase (sialic acid synthase) Neighboring gene tripartite motif-containing 14 Neighboring gene uncharacterized LOC108168940

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC103080

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    inner ear development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    roof of mouth development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    vasculature development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ventricular system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    acidic leucine-rich nuclear phosphoprotein 32 family member B
    Names
    acidic protein rich in leucines
    proliferation related acidic leucine rich protein PAL31

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_130889.3NP_570959.1  acidic leucine-rich nuclear phosphoprotein 32 family member B

      See identical proteins and their annotated locations for NP_570959.1

      Status: VALIDATED

      Source sequence(s)
      AK165807, CJ053476, CK623910
      Consensus CDS
      CCDS18151.1
      UniProtKB/Swiss-Prot
      Q9EST5
      Related
      ENSMUSP00000099990.4, ENSMUST00000102926.4
      Conserved Domains (3) summary
      COG4886
      Location:16115
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00035
      Location:90113
      LRR_NTF; leucine-rich repeat [structural motif]
      pfam14580
      Location:71146
      LRR_9; Leucine-rich repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      46451117..46472532
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250089.2XP_011248391.1  acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1

      Conserved Domains (3) summary
      smart00446
      Location:99117
      LRRcap; occurring C-terminal to leucine-rich repeats
      sd00035
      Location:6184
      LRR_NTF; leucine-rich repeat [structural motif]
      pfam12799
      Location:5998
      LRR_4; Leucine Rich repeats (2 copies)
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