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    Nob1 NIN1/RPN12 binding protein 1 homolog [ Mus musculus (house mouse) ]

    Gene ID: 67619, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nob1provided by MGI
    Official Full Name
    NIN1/RPN12 binding protein 1 homologprovided by MGI
    Primary source
    MGI:MGI:1914869
    See related
    Ensembl:ENSMUSG00000003848
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    No; ART; ART-4; Nob1p; Psmd8; Psmd8bp1; 1700021I09Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 29.2), limb E14.5 (RPKM 26.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Nob1 in Genome Data Viewer
    Location:
    8; 8 D3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (108139121..108151670, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (107412489..107425038, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (109936389..109948938, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene nuclear factor of activated T cells 5 Neighboring gene predicted gene, 51546 Neighboring gene NAD(P)H dehydrogenase, quinone 1 Neighboring gene ribosomal protein S26, pseudogene 1 Neighboring gene predicted gene, 39241 Neighboring gene WW domain containing E3 ubiquitin protein ligase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118441, MGC144649, MGC144650

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables endoribonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables endoribonuclease activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cleavage involved in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within maturation of SSU-rRNA ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    acts_upstream_of_or_within ribosomal small subunit biogenesis ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    acts_upstream_of_or_within visual perception IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in nucleolus ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in nucleus ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    part_of preribosome, small subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    RNA-binding protein NOB1
    Names
    PSMD8 binding protein 1
    nin one binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026277.3NP_080553.1  RNA-binding protein NOB1

      See identical proteins and their annotated locations for NP_080553.1

      Status: VALIDATED

      Source sequence(s)
      AC158364
      Consensus CDS
      CCDS22649.1
      UniProtKB/Swiss-Prot
      Q8BW10
      UniProtKB/TrEMBL
      Q148S3
      Related
      ENSMUSP00000003946.9, ENSMUST00000003946.9
      Conserved Domains (4) summary
      cd09876
      Location:7115
      PIN_Nob1; PIN domain of eukaryotic ribosome assembly factor Nob1 and archaeal UPF0129 protein Ta0041-like homologs
      COG1439
      Location:8292
      Nob1; rRNA maturation endonuclease Nob1 [Translation, ribosomal structure and biogenesis]
      pfam15017
      Location:135211
      AF1Q; Drug resistance and apoptosis regulator
      pfam08772
      Location:251323
      NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      108139121..108151670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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