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    Nob1 NIN1/RPN12 binding protein 1 homolog [ Mus musculus (house mouse) ]

    Gene ID: 67619, updated on 9-Sep-2018

    Summary

    Official Symbol
    Nob1provided by MGI
    Official Full Name
    NIN1/RPN12 binding protein 1 homologprovided by MGI
    Primary source
    MGI:MGI:1914869
    See related
    Ensembl:ENSMUSG00000003848 Vega:OTTMUSG00000035977
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ART-4; Nob1p; Psmd8bp1; 1700021I09Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 29.2), limb E14.5 (RPKM 26.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Nob1 in Genome Data Viewer
    Location:
    8; 8 D3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (107412489..107425038, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (109936389..109948938, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene nuclear factor of activated T cells 5 Neighboring gene NAD(P)H dehydrogenase, quinone 1 Neighboring gene ribosomal protein S26, pseudogene 1 Neighboring gene predicted gene, 39241 Neighboring gene WW domain containing E3 ubiquitin protein ligase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    • Ribosome biogenesis in eukaryotes, organism-specific biosystem (from KEGG)
      Ribosome biogenesis in eukaryotes, organism-specific biosystemRibosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It...
    • Ribosome biogenesis in eukaryotes, conserved biosystem (from KEGG)
      Ribosome biogenesis in eukaryotes, conserved biosystemRibosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It...

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118441, MGC144649, MGC144650

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    endoribonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoribonuclease activity ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cleavage involved in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    maturation of SSU-rRNA ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    ribosomal small subunit biogenesis ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    visual perception IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    nucleolus ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    nucleus ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    preribosome, small subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    RNA-binding protein NOB1
    Names
    PSMD8 binding protein 1
    nin one binding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026277.3NP_080553.1  RNA-binding protein NOB1

      See identical proteins and their annotated locations for NP_080553.1

      Status: PROVISIONAL

      Source sequence(s)
      AC158364
      Consensus CDS
      CCDS22649.1
      UniProtKB/Swiss-Prot
      Q8BW10
      UniProtKB/TrEMBL
      Q148S3
      Related
      ENSMUSP00000003946.8, OTTMUSP00000050998, ENSMUST00000003946.8, OTTMUST00000092320
      Conserved Domains (4) summary
      cd09876
      Location:7115
      PIN_Nob1; PIN domain of eukaryotic ribosome assembly factor Nob1 and archaeal UPF0129 protein Ta0041-like homologs
      COG1439
      Location:8292
      Nob1; rRNA maturation endonuclease Nob1 [Translation, ribosomal structure and biogenesis]
      pfam15017
      Location:135211
      AF1Q; Drug resistance and apoptosis regulator
      pfam08772
      Location:251323
      NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      107412489..107425038 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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