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    Cpeb4 cytoplasmic polyadenylation element binding protein 4 [ Mus musculus (house mouse) ]

    Gene ID: 67579, updated on 22-Aug-2021

    Summary

    Official Symbol
    Cpeb4provided by MGI
    Official Full Name
    cytoplasmic polyadenylation element binding protein 4provided by MGI
    Primary source
    MGI:MGI:1914829
    See related
    Ensembl:ENSMUSG00000020300
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cpeb-4; Cpe-bp4; mCPEB-4
    Expression
    Ubiquitous expression in liver E14 (RPKM 15.0), liver E14.5 (RPKM 14.5) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cpeb4 in Genome Data Viewer
    Location:
    11; 11 A4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (31820911..31885635)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (31870104..31935635)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (31772211..31831577)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA D630024D03 gene Neighboring gene predicted gene, 39675 Neighboring gene predicted gene 12107 Neighboring gene von Hippel-Lindau binding protein 1 pseudogene Neighboring gene RIKEN cDNA 4930524B15 gene Neighboring gene S-adenosylmethionine decarboxylase, pseudogene 3 pseudogene Neighboring gene predicted gene, 35267

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • mKIAA1673, 4930447D24Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation factor activity, RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation repressor activity, mRNA regulatory element binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of messenger ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cytoplasmic polyadenylation element-binding protein 4
    Names
    CPE-binding protein 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290676.1NP_001277605.1  cytoplasmic polyadenylation element-binding protein 4 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
      Source sequence(s)
      AI845839, AK162101, BC079599, CD803291
      UniProtKB/TrEMBL
      Q3TSF0
      Conserved Domains (3) summary
      cd12724
      Location:464555
      RRM1_CPEB2_like; RNA recognition motif 1 in cytoplasmic polyadenylation element-binding protein CPEB-2, CPEB-3, CPEB-4 and similar protiens
      cd12726
      Location:572652
      RRM2_CPEB2_like; RNA recognition motif 2 found in cytoplasmic polyadenylation element-binding protein CPEB-2, CPEB-3, CPEB-4 and similar protiens
      pfam16366
      Location:647708
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    2. NM_001290678.1NP_001277607.1  cytoplasmic polyadenylation element-binding protein 4 isoform 3

      See identical proteins and their annotated locations for NP_001277607.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two exons in the central coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.
      Source sequence(s)
      AI845839, AK162101, BC079599, CD803291
      UniProtKB/Swiss-Prot
      Q7TN98
      UniProtKB/TrEMBL
      Q3TSF0
      Conserved Domains (3) summary
      cd12724
      Location:447538
      RRM1_CPEB2_like; RNA recognition motif 1 in cytoplasmic polyadenylation element-binding protein CPEB-2, CPEB-3, CPEB-4 and similar protiens
      cd12726
      Location:555635
      RRM2_CPEB2_like; RNA recognition motif 2 found in cytoplasmic polyadenylation element-binding protein CPEB-2, CPEB-3, CPEB-4 and similar protiens
      pfam16366
      Location:630691
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    3. NM_026252.4NP_080528.2  cytoplasmic polyadenylation element-binding protein 4 isoform 1

      See identical proteins and their annotated locations for NP_080528.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AI845839, AK162101, BC079599, CF182456
      Consensus CDS
      CCDS24514.1
      UniProtKB/Swiss-Prot
      Q7TN98
      UniProtKB/TrEMBL
      Q3TSF0
      Related
      ENSMUSP00000020543.7, ENSMUST00000020543.13
      Conserved Domains (3) summary
      cd12724
      Location:472563
      RRM1_CPEB2_like; RNA recognition motif 1 in cytoplasmic polyadenylation element-binding protein CPEB-2, CPEB-3, CPEB-4 and similar protiens
      cd12726
      Location:580660
      RRM2_CPEB2_like; RNA recognition motif 2 found in cytoplasmic polyadenylation element-binding protein CPEB-2, CPEB-3, CPEB-4 and similar protiens
      pfam16366
      Location:655716
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      31820911..31885635
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514793.3XP_006514856.1  cytoplasmic polyadenylation element-binding protein 4 isoform X1

      UniProtKB/TrEMBL
      Q5SU48
      Related
      ENSMUSP00000105039.3, ENSMUST00000109412.9
      Conserved Domains (3) summary
      cd12724
      Location:455546
      RRM1_CPEB2_like; RNA recognition motif 1 in cytoplasmic polyadenylation element-binding protein CPEB-2, CPEB-3, CPEB-4 and similar protiens
      cd12726
      Location:563643
      RRM2_CPEB2_like; RNA recognition motif 2 found in cytoplasmic polyadenylation element-binding protein CPEB-2, CPEB-3, CPEB-4 and similar protiens
      pfam16366
      Location:638699
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
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