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    Gstcd glutathione S-transferase, C-terminal domain containing [ Mus musculus (house mouse) ]

    Gene ID: 67553, updated on 23-May-2018

    Summary

    Official Symbol
    Gstcdprovided by MGI
    Official Full Name
    glutathione S-transferase, C-terminal domain containingprovided by MGI
    Primary source
    MGI:MGI:1914803
    See related
    Ensembl:ENSMUSG00000028018 Vega:OTTMUSG00000023354
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933434L15Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 7.0), testis adult (RPKM 6.2) and 27 other tissues See more
    Orthologs

    Genomic context

    See Gstcd in Genome Data Viewer
    Location:
    3; 3 G3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (132982550..133091833, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (132645514..132754704, complement)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 29811 Neighboring gene heat shock protein 90 alpha (cytosolic), class B member 1 pseudogene Neighboring gene nephronectin Neighboring gene TIP41, TOR signalling pathway regulator-like pseudogene Neighboring gene integrator complex subunit 12 Neighboring gene Rho guanine nucleotide exchange factor (GEF) 38

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    General gene information

    Homology

    Clone Names

    • MGC74393

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glutathione S-transferase C-terminal domain-containing protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356309.1NP_001343238.1  glutathione S-transferase C-terminal domain-containing protein

      Status: VALIDATED

      Source sequence(s)
      AC124593, BC061240
      Conserved Domains (2) summary
      cl02776
      Location:271330
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
      cl17173
      Location:424542
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    2. NM_026231.3NP_080507.2  glutathione S-transferase C-terminal domain-containing protein

      See identical proteins and their annotated locations for NP_080507.2

      Status: VALIDATED

      Source sequence(s)
      AC124593, BC047136, BY740821
      Consensus CDS
      CCDS17847.1
      UniProtKB/Swiss-Prot
      Q5RL51
      Related
      ENSMUSP00000029651.4, OTTMUSP00000027240, ENSMUST00000029651.10
      Conserved Domains (2) summary
      cl02776
      Location:271330
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
      cl17173
      Location:424542
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      132982550..133091833 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501938.3XP_006502001.1  glutathione S-transferase C-terminal domain-containing protein isoform X1

      See identical proteins and their annotated locations for XP_006502001.1

      UniProtKB/Swiss-Prot
      Q5RL51
      Conserved Domains (2) summary
      cd00299
      Location:262323
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
      pfam13847
      Location:441510
      Methyltransf_31; Methyltransferase domain
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