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    Ppfibp1 PTPRF interacting protein, binding protein 1 (liprin beta 1) [ Mus musculus (house mouse) ]

    Gene ID: 67533, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ppfibp1provided by MGI
    Official Full Name
    PTPRF interacting protein, binding protein 1 (liprin beta 1)provided by MGI
    Primary source
    MGI:MGI:1914783
    See related
    Ensembl:ENSMUSG00000016487
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW214454; AW261454; 4632409B19Rik
    Expression
    Ubiquitous expression in bladder adult (RPKM 15.6), limb E14.5 (RPKM 10.2) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ppfibp1 in Genome Data Viewer
    Location:
    6; 6 G3
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (146788107..146933523)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (146886609..147032025)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (146837016..146980545)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene aryl hydrocarbon receptor nuclear translocator-like 2 Neighboring gene single-pass membrane protein with coiled-coil domains 2 Neighboring gene RIKEN cDNA 1700034J05 gene Neighboring gene predicted gene, 35876 Neighboring gene RAB15 effector protein Neighboring gene mitochondrial ribosomal protein S35

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in neuromuscular junction development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in presynaptic active zone IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    liprin-beta-1
    Names
    PTPRF-interacting protein-binding protein 1
    protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170433.1NP_001163904.1  liprin-beta-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC153575, AC156394, BC072603
      Consensus CDS
      CCDS51958.1
      UniProtKB/Swiss-Prot
      Q8C8U0
      Related
      ENSMUSP00000107250.3, ENSMUST00000111623.9
      Conserved Domains (8) summary
      cd09563
      Location:614677
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:688750
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:773844
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:614678
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      pfam14662
      Location:106314
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      cl21478
      Location:213307
      ATP-synt_B; ATP synthase B/B' CF(0)
      cl23720
      Location:134255
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    2. NM_001355728.1NP_001342657.1  liprin-beta-1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC153575, AC156394
      Conserved Domains (4) summary
      cd09563
      Location:666729
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:740802
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:825896
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:100378
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    3. NM_001355729.1NP_001342658.1  liprin-beta-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC153575, AC156394
      Consensus CDS
      CCDS39715.1
      Conserved Domains (4) summary
      cd09563
      Location:603666
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:677739
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:762833
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      cl25732
      Location:47310
      SMC_N; RecF/RecN/SMC N terminal domain
    4. NM_026221.2NP_080497.1  liprin-beta-1 isoform 2

      See identical proteins and their annotated locations for NP_080497.1

      Status: VALIDATED

      Source sequence(s)
      AC153575, AC156394, BC072603
      Consensus CDS
      CCDS39715.1
      UniProtKB/Swiss-Prot
      Q8C8U0
      Related
      ENSMUSP00000016631.8, ENSMUST00000016631.14
      Conserved Domains (4) summary
      cd09563
      Location:603666
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:677739
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:762833
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      cl25732
      Location:47310
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      146788107..146933523
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241625.2XP_011239927.1  liprin-beta-1 isoform X1

      See identical proteins and their annotated locations for XP_011239927.1

      Conserved Domains (4) summary
      cd09563
      Location:666729
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:740802
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:825896
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:100378
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    2. XM_011241624.2XP_011239926.1  liprin-beta-1 isoform X1

      See identical proteins and their annotated locations for XP_011239926.1

      Conserved Domains (4) summary
      cd09563
      Location:666729
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:740802
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:825896
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:100378
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    3. XM_006507098.4XP_006507161.1  liprin-beta-1 isoform X4

      Conserved Domains (4) summary
      cd09563
      Location:655718
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:729791
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:814885
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:100378
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    4. XM_006507096.3XP_006507159.1  liprin-beta-1 isoform X2

      Conserved Domains (4) summary
      cd09563
      Location:656719
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:730792
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:815886
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:100378
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    5. XM_011241627.2XP_011239929.1  liprin-beta-1 isoform X5

      Conserved Domains (4) summary
      cd09563
      Location:645708
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:719781
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:804875
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:100378
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    6. XM_006507097.3XP_006507160.1  liprin-beta-1 isoform X3

      Conserved Domains (4) summary
      cd09563
      Location:655718
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:729791
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:814885
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47341
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    7. XM_006507101.3XP_006507164.1  liprin-beta-1 isoform X13

      Conserved Domains (4) summary
      cd09563
      Location:644707
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:718780
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:803874
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47341
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    8. XM_006507099.3XP_006507162.1  liprin-beta-1 isoform X6

      Conserved Domains (4) summary
      cd09563
      Location:645708
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:719781
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:804875
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47341
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    9. XM_036152273.1XP_036008166.1  liprin-beta-1 isoform X8

      Conserved Domains (4) summary
      cd09563
      Location:634697
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:708770
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:793864
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47341
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    10. XM_006507102.3XP_006507165.1  liprin-beta-1 isoform X7

      Conserved Domains (4) summary
      cd09563
      Location:635698
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:709771
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:794865
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47321
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    11. XM_036152275.1XP_036008168.1  liprin-beta-1 isoform X10

      Conserved Domains (4) summary
      cd09563
      Location:624687
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:698760
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:783854
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47321
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    12. XM_006507103.3XP_006507166.1  liprin-beta-1 isoform X9

      Conserved Domains (4) summary
      cd09563
      Location:624687
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:698760
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:783854
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47310
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    13. XM_011241629.2XP_011239931.1  liprin-beta-1 isoform X12

      Conserved Domains (4) summary
      cd09563
      Location:613676
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:687749
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:772843
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47310
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    14. XM_011241628.2XP_011239930.1  liprin-beta-1 isoform X11

      Conserved Domains (4) summary
      cd09563
      Location:614677
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:688750
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:773844
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47310
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    15. XM_036152272.1XP_036008165.1  liprin-beta-1 isoform X4

      Conserved Domains (4) summary
      cd09563
      Location:655718
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:729791
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:814885
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:100378
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    16. XM_036152274.1XP_036008167.1  liprin-beta-1 isoform X8

      Conserved Domains (4) summary
      cd09563
      Location:634697
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:708770
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:793864
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47341
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    17. XM_030255565.1XP_030111425.1  liprin-beta-1 isoform X7

      Conserved Domains (4) summary
      cd09563
      Location:635698
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:709771
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:794865
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:47321
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    18. XM_011241626.3XP_011239928.1  liprin-beta-1 isoform X1

      See identical proteins and their annotated locations for XP_011239928.1

      Conserved Domains (4) summary
      cd09563
      Location:666729
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:740802
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:825896
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      COG1196
      Location:100378
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
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