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    Ppfibp1 PTPRF interacting protein, binding protein 1 (liprin beta 1) [ Mus musculus (house mouse) ]

    Gene ID: 67533, updated on 7-Aug-2018

    Summary

    Official Symbol
    Ppfibp1provided by MGI
    Official Full Name
    PTPRF interacting protein, binding protein 1 (liprin beta 1)provided by MGI
    Primary source
    MGI:MGI:1914783
    See related
    Ensembl:ENSMUSG00000016487 Vega:OTTMUSG00000022991
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW214454; AW261454; 4632409B19Rik
    Expression
    Ubiquitous expression in bladder adult (RPKM 15.6), limb E14.5 (RPKM 10.2) and 24 other tissues See more
    Orthologs

    Genomic context

    See Ppfibp1 in Genome Data Viewer
    Location:
    6; 6 G3
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (146888080..147032025)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (146837016..146980545)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene aryl hydrocarbon receptor nuclear translocator-like 2 Neighboring gene single-pass membrane protein with coiled-coil domains 2 Neighboring gene RIKEN cDNA 1700034J05 gene Neighboring gene predicted gene, 35876 Neighboring gene RAB15 effector protein Neighboring gene mitochondrial ribosomal protein S35

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    liprin-beta-1
    Names
    PTPRF-interacting protein-binding protein 1
    protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170433.1NP_001163904.1  liprin-beta-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC153575, AC156394, BC072603
      Consensus CDS
      CCDS51958.1
      UniProtKB/Swiss-Prot
      Q8C8U0
      Related
      ENSMUSP00000107250.2, OTTMUSP00000026501, ENSMUST00000111623.8, OTTMUST00000055356
      Conserved Domains (8) summary
      cd09563
      Location:614677
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:688750
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:773844
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:614678
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      pfam14662
      Location:106314
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      cl21478
      Location:213307
      ATP-synt_B; ATP synthase B/B' CF(0)
      cl23720
      Location:134255
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    2. NM_001355728.1NP_001342657.1  liprin-beta-1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC153575, AC156394
    3. NM_001355729.1NP_001342658.1  liprin-beta-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC153575, AC156394
      Conserved Domains (4) summary
      cd09563
      Location:603666
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:677739
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:762833
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      cl25732
      Location:47310
      SMC_N; RecF/RecN/SMC N terminal domain
    4. NM_026221.2NP_080497.1  liprin-beta-1 isoform 2

      See identical proteins and their annotated locations for NP_080497.1

      Status: VALIDATED

      Source sequence(s)
      AC153575, AC156394, BC072603
      Consensus CDS
      CCDS39715.1
      UniProtKB/Swiss-Prot
      Q8C8U0
      Related
      ENSMUSP00000016631.7, OTTMUSP00000026500, ENSMUST00000016631.13, OTTMUST00000055355
      Conserved Domains (4) summary
      cd09563
      Location:603666
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:677739
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:762833
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      cl25732
      Location:47310
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      146888080..147032025
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241625.1XP_011239927.1  liprin-beta-1 isoform X1

      See identical proteins and their annotated locations for XP_011239927.1

      Conserved Domains (7) summary
      cd09563
      Location:666729
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:740802
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:825896
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:666730
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
      cl21478
      Location:253338
      ATP-synt_B; ATP synthase B/B' CF(0)
    2. XM_011241624.1XP_011239926.1  liprin-beta-1 isoform X1

      See identical proteins and their annotated locations for XP_011239926.1

      Conserved Domains (7) summary
      cd09563
      Location:666729
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:740802
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:825896
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:666730
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
      cl21478
      Location:253338
      ATP-synt_B; ATP synthase B/B' CF(0)
    3. XM_006507096.2XP_006507159.1  liprin-beta-1 isoform X2

      Conserved Domains (7) summary
      cd09563
      Location:656719
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:730792
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:815886
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:656720
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
      cl21478
      Location:253338
      ATP-synt_B; ATP synthase B/B' CF(0)
    4. XM_011241627.1XP_011239929.1  liprin-beta-1 isoform X6

      Conserved Domains (7) summary
      cd09563
      Location:645708
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:719781
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:804875
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:645709
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
      cl21478
      Location:253338
      ATP-synt_B; ATP synthase B/B' CF(0)
    5. XM_006507097.2XP_006507160.1  liprin-beta-1 isoform X3

      Conserved Domains (6) summary
      cd09563
      Location:655718
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:729791
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:814885
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:655719
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
    6. XM_006507101.2XP_006507164.1  liprin-beta-1 isoform X11

      Conserved Domains (6) summary
      cd09563
      Location:644707
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:718780
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:803874
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:644708
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
    7. XM_006507099.2XP_006507162.1  liprin-beta-1 isoform X5

      Conserved Domains (6) summary
      cd09563
      Location:645708
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:719781
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:804875
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:645709
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
    8. XM_006507102.2XP_006507165.1  liprin-beta-1 isoform X7

      Conserved Domains (8) summary
      cd09563
      Location:635698
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:709771
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:794865
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:635699
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      pfam14662
      Location:106314
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      cl21478
      Location:213307
      ATP-synt_B; ATP synthase B/B' CF(0)
      cl23720
      Location:134255
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    9. XM_006507103.2XP_006507166.1  liprin-beta-1 isoform X8

      Conserved Domains (7) summary
      cd09563
      Location:624687
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:698760
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:783854
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:624688
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      pfam14662
      Location:106303
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      cl23720
      Location:134255
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    10. XM_011241629.1XP_011239931.1  liprin-beta-1 isoform X12

      Conserved Domains (7) summary
      cd09563
      Location:613676
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:687749
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:772843
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:613677
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      pfam14662
      Location:106303
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      cl23720
      Location:134255
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    11. XM_011241628.1XP_011239930.1  liprin-beta-1 isoform X9

      Conserved Domains (7) summary
      cd09563
      Location:614677
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:688750
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:773844
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:614678
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      pfam14662
      Location:106303
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      cl23720
      Location:134255
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    12. XM_006507095.3XP_006507158.1  liprin-beta-1 isoform X1

      Conserved Domains (7) summary
      cd09563
      Location:666729
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:740802
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:825896
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:666730
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
      cl21478
      Location:253338
      ATP-synt_B; ATP synthase B/B' CF(0)
    13. XM_006507098.3XP_006507161.1  liprin-beta-1 isoform X4

      Conserved Domains (7) summary
      cd09563
      Location:655718
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:729791
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:814885
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:655719
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
      cl21478
      Location:253338
      ATP-synt_B; ATP synthase B/B' CF(0)
    14. XM_017321719.1XP_017177208.1  liprin-beta-1 isoform X10

      UniProtKB/Swiss-Prot
      Q8C8U0
      Conserved Domains (4) summary
      cd09563
      Location:603666
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:677739
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:762833
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      cl25732
      Location:47310
      SMC_N; RecF/RecN/SMC N terminal domain
    15. XM_011241626.2XP_011239928.1  liprin-beta-1 isoform X1

      See identical proteins and their annotated locations for XP_011239928.1

      Conserved Domains (7) summary
      cd09563
      Location:666729
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:740802
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:825896
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:666730
      SAM; Sterile alpha motif
      pfam01519
      Location:105156
      DUF16; Protein of unknown function DUF16
      cl19219
      Location:203281
      DUF342; Protein of unknown function (DUF342)
      cl21478
      Location:253338
      ATP-synt_B; ATP synthase B/B' CF(0)

    Reference GRCm38.p4 NOD/ShiLtJ

    Genomic

    1. NT_166305.2 Reference GRCm38.p4 NOD/ShiLtJ

      Range
      3388127..3526843
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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