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    Tvp23b trans-golgi network vesicle protein 23B [ Mus musculus (house mouse) ]

    Gene ID: 67510, updated on 23-May-2018

    Summary

    Official Symbol
    Tvp23bprovided by MGI
    Official Full Name
    trans-golgi network vesicle protein 23Bprovided by MGI
    Primary source
    MGI:MGI:1914760
    See related
    Ensembl:ENSMUSG00000014177 Vega:OTTMUSG00000005878
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam18b; Fam18b1; 1810036I24Rik
    Expression
    Ubiquitous expression in bladder adult (RPKM 15.5), placenta adult (RPKM 15.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tvp23b in Genome Data Viewer
    Location:
    11; 11 B2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (62879435..62895186)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (62692992..62708686)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 16 Neighboring gene F-box and WD-40 domain protein 10 Neighboring gene trans-golgi network vesicle protein 23B, opposite strand Neighboring gene predicted gene, 36614

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Golgi apparatus membrane protein TVP23 homolog B
    Names
    family with sequence similarity 18, member B
    ortholog of human family with sequence similarity 18 member B FAM18B
    protein FAM18B1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356520.1NP_001343449.1  Golgi apparatus membrane protein TVP23 homolog B isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two consecutive alternate in-frame exons in the 3' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1.
      Source sequence(s)
      AK007707, AK050027, AK077277, BP757155, CK334592
      Conserved Domains (1) summary
      pfam05832
      Location:32130
      DUF846; Eukaryotic protein of unknown function (DUF846)
    2. NM_001356521.1NP_001343450.1  Golgi apparatus membrane protein TVP23 homolog B isoform 3 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, uses a downstream start codon and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 3, which is shorter than isoform 1.
      Source sequence(s)
      AK007707, AK050027, BP757155, BY113761
      Conserved Domains (1) summary
      pfam05832
      Location:1110
      DUF846; Eukaryotic protein of unknown function (DUF846)
    3. NM_026210.5NP_080486.1  Golgi apparatus membrane protein TVP23 homolog B isoform 1

      See identical proteins and their annotated locations for NP_080486.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AK007707, AK050027, AK150936, BP757155
      Consensus CDS
      CCDS24834.1
      UniProtKB/Swiss-Prot
      Q9D8T4
      Related
      ENSMUSP00000014321.4, OTTMUSP00000006078, ENSMUST00000014321.4
      Conserved Domains (1) summary
      pfam05832
      Location:32174
      DUF846; Eukaryotic protein of unknown function (DUF846)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      62879435..62895186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534002.2XP_006534065.1  Golgi apparatus membrane protein TVP23 homolog B isoform X1

      Conserved Domains (1) summary
      pfam05832
      Location:32130
      DUF846; Eukaryotic protein of unknown function (DUF846)
    2. XM_006534003.2XP_006534066.1  Golgi apparatus membrane protein TVP23 homolog B isoform X2

      Conserved Domains (1) summary
      pfam05832
      Location:1110
      DUF846; Eukaryotic protein of unknown function (DUF846)
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