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    Ccar1 cell division cycle and apoptosis regulator 1 [ Mus musculus (house mouse) ]

    Gene ID: 67500, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ccar1provided by MGI
    Official Full Name
    cell division cycle and apoptosis regulator 1provided by MGI
    Primary source
    MGI:MGI:1914750
    See related
    Ensembl:ENSMUSG00000020074
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Carp1; 2610511G16Rik; 9430036H15Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 29.0), CNS E14 (RPKM 18.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ccar1 in Genome Data Viewer
    Location:
    10; 10 B4
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (62743928..62792368, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (62206676..62255116, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene storkhead box 1 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene microRNA 7215 Neighboring gene small nucleolar RNA, C/D box 98 Neighboring gene tet methylcytosine dioxygenase 1 Neighboring gene solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16 Neighboring gene ribosomal protein 10 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC90759

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA polymerase II distal enhancer sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear receptor transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear receptor transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription coactivator activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear envelope lumen ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    cell division cycle and apoptosis regulator protein 1
    Names
    CARP-1
    cell cycle and apoptosis regulatory protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026201.3NP_080477.1  cell division cycle and apoptosis regulator protein 1

      See identical proteins and their annotated locations for NP_080477.1

      Status: VALIDATED

      Source sequence(s)
      AC122539
      Consensus CDS
      CCDS35922.1
      UniProtKB/Swiss-Prot
      Q8CH18
      Related
      ENSMUSP00000151895.1, ENSMUST00000219527.1
      Conserved Domains (4) summary
      smart00513
      Location:634667
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      PHA03356
      Location:278310
      PHA03356; tegument protein UL11; Provisional
      pfam14443
      Location:479598
      DBC1; DBC1
      pfam14444
      Location:149201
      S1-like; S1-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      62743928..62792368 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513997.2XP_006514060.1  cell division cycle and apoptosis regulator protein 1 isoform X2

      UniProtKB/Swiss-Prot
      Q8CH18
      Conserved Domains (3) summary
      PHA03356
      Location:278310
      PHA03356; tegument protein UL11; Provisional
      pfam14443
      Location:479598
      DBC1; DBC1
      pfam14444
      Location:149201
      S1-like; S1-like
    2. XM_011243537.2XP_011241839.1  cell division cycle and apoptosis regulator protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011241839.1

      UniProtKB/Swiss-Prot
      Q8CH18
      Related
      ENSMUSP00000020268.5, ENSMUST00000020268.6
      Conserved Domains (4) summary
      smart00513
      Location:634667
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      PHA03356
      Location:278310
      PHA03356; tegument protein UL11; Provisional
      pfam14443
      Location:479598
      DBC1; DBC1
      pfam14444
      Location:149201
      S1-like; S1-like
    3. XM_006513994.3XP_006514057.1  cell division cycle and apoptosis regulator protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006514057.1

      UniProtKB/Swiss-Prot
      Q8CH18
      Conserved Domains (4) summary
      smart00513
      Location:634667
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      PHA03356
      Location:278310
      PHA03356; tegument protein UL11; Provisional
      pfam14443
      Location:479598
      DBC1; DBC1
      pfam14444
      Location:149201
      S1-like; S1-like
    4. XM_006513996.3XP_006514059.1  cell division cycle and apoptosis regulator protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006514059.1

      UniProtKB/Swiss-Prot
      Q8CH18
      Conserved Domains (4) summary
      smart00513
      Location:634667
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      PHA03356
      Location:278310
      PHA03356; tegument protein UL11; Provisional
      pfam14443
      Location:479598
      DBC1; DBC1
      pfam14444
      Location:149201
      S1-like; S1-like
    5. XM_006513995.3XP_006514058.1  cell division cycle and apoptosis regulator protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006514058.1

      UniProtKB/Swiss-Prot
      Q8CH18
      Conserved Domains (4) summary
      smart00513
      Location:634667
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      PHA03356
      Location:278310
      PHA03356; tegument protein UL11; Provisional
      pfam14443
      Location:479598
      DBC1; DBC1
      pfam14444
      Location:149201
      S1-like; S1-like
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