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    Dhx40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [ Mus musculus (house mouse) ]

    Gene ID: 67487, updated on 31-Jan-2019

    Summary

    Official Symbol
    Dhx40provided by MGI
    Official Full Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 40provided by MGI
    Primary source
    MGI:MGI:1914737
    See related
    Ensembl:ENSMUSG00000018425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PAD; DDX40; ARG147; 2410016C14Rik
    Expression
    Ubiquitous expression in bladder adult (RPKM 11.1), testis adult (RPKM 10.7) and 25 other tissues See more
    Orthologs

    Genomic context

    See Dhx40 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (86768849..86807936, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (86582351..86621162, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene peptidyl-tRNA hydrolase 2 Neighboring gene clathrin, heavy polypeptide (Hc) Neighboring gene predicted gene, 42085 Neighboring gene predicted gene, 33742 Neighboring gene predicted gene, 38942 Neighboring gene predicted gene, 46290

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATP-dependent 3'-5' RNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    probable ATP-dependent RNA helicase DHX40
    Names
    DEAH box protein 40
    NP_080467.3
    XP_017170207.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026191.2NP_080467.3  probable ATP-dependent RNA helicase DHX40

      See identical proteins and their annotated locations for NP_080467.3

      Status: VALIDATED

      Source sequence(s)
      AK010512, BP771378, BY329362, CF749423
      Consensus CDS
      CCDS36268.1
      UniProtKB/Swiss-Prot
      Q6PE54
      Related
      ENSMUSP00000018569.6, ENSMUST00000018569.13
      Conserved Domains (5) summary
      smart00490
      Location:312399
      HELICc; helicase superfamily c-terminal domain
      smart00487
      Location:48236
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:469557
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:78213
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam07717
      Location:591699
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      86768849..86807936 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314718.1XP_017170207.1  probable ATP-dependent RNA helicase DHX40 isoform X1

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