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    Ero1lb ERO1-like beta (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 67475, updated on 23-May-2018

    Summary

    Official Symbol
    Ero1lbprovided by MGI
    Official Full Name
    ERO1-like beta (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1914725
    See related
    Ensembl:ENSMUSG00000057069
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ero1b; AI447560; ero1-beta; 1300013B24Rik; 1700065B09Rik
    Expression
    Broad expression in testis adult (RPKM 15.0), spleen adult (RPKM 5.1) and 24 other tissues See more
    Orthologs

    Genomic context

    See Ero1lb in Genome Data Viewer
    Location:
    13; 13 A1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (12565808..12609533)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (12658150..12701795)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene lectin, galactose binding, soluble 8 Neighboring gene EDAR (ectodysplasin-A receptor)-associated death domain Neighboring gene G protein-coupled receptor 137B, pseudogene Neighboring gene nidogen-1-like Neighboring gene NHP2-like protein 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
    • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...

    General gene information

    Markers

    Homology

    Clone Names

    • MGC77955

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    protein disulfide isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein disulfide oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein disulfide oxidoreductase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    4-hydroxyproline metabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cell redox homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    extracellular matrix organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    glucose homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    insulin processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    protein folding in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein maturation by protein folding IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    protein maturation by protein folding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ERO1-like protein beta
    Names
    ERO1-L-beta
    endoplasmic oxidoreductase 1 beta
    endoplasmic oxidoreductin-1-like protein B
    endoplasmic reticulum oxidoreductase beta
    endoplasmic reticulum oxidoreductin-1-like protein B
    oxidoreductin-1-L-beta

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026184.2NP_080460.2  ERO1-like protein beta precursor

      See identical proteins and their annotated locations for NP_080460.2

      Status: PROVISIONAL

      Source sequence(s)
      BC058721
      Consensus CDS
      CCDS36594.1
      UniProtKB/Swiss-Prot
      Q8R2E9
      Related
      ENSMUSP00000071864.6, ENSMUST00000071973.7
      Conserved Domains (1) summary
      pfam04137
      Location:56454
      ERO1; Endoplasmic Reticulum Oxidoreductin 1 (ERO1)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      12565808..12609533
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516730.3XP_006516793.1  ERO1-like protein beta isoform X1

      UniProtKB/TrEMBL
      A0A1Y7VNF4
      Related
      ENSMUSP00000152393.1, ENSMUST00000221560.1
      Conserved Domains (1) summary
      pfam04137
      Location:56450
      ERO1; Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
    2. XM_006516731.3XP_006516794.1  ERO1-like protein beta isoform X2

      Conserved Domains (1) summary
      pfam04137
      Location:56454
      ERO1; Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
    3. XM_006516732.2XP_006516795.1  ERO1-like protein beta isoform X3

      Related
      ENSMUSP00000152543.1, ENSMUST00000220811.1
      Conserved Domains (1) summary
      pfam04137
      Location:56448
      ERO1; Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
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