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    Sf3a1 splicing factor 3a, subunit 1 [ Mus musculus (house mouse) ]

    Gene ID: 67465, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sf3a1provided by MGI
    Official Full Name
    splicing factor 3a, subunit 1provided by MGI
    Primary source
    MGI:MGI:1914715
    See related
    Ensembl:ENSMUSG00000002129
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI159724; 1200014H24Rik; 5930416L09Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 27.8), thymus adult (RPKM 22.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Sf3a1 in Genome Data Viewer
    Location:
    11; 11 A1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (4110354..4132541)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (4160354..4182541)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (4060357..4082544)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene transformer 2 beta homolog pseudogene Neighboring gene ring finger protein 215 Neighboring gene microRNA 3060 Neighboring gene coiled-coil domain containing 157 Neighboring gene TBC1 domain family, member 10a Neighboring gene cytosolic arginine sensor for mTORC1 subunit 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Transgenic (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in U2-type prespliceosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of U2 snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of U2-type prespliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    splicing factor 3A subunit 1
    Names
    SF3a120
    splicing factor 3 subunit 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026175.5NP_080451.4  splicing factor 3A subunit 1

      See identical proteins and their annotated locations for NP_080451.4

      Status: VALIDATED

      Source sequence(s)
      AI115048, AK028829, AK030115, AK160061, AL807825
      Consensus CDS
      CCDS24380.1
      UniProtKB/Swiss-Prot
      Q8K4Z5
      UniProtKB/TrEMBL
      Q3TVM1
      Related
      ENSMUSP00000002198.4, ENSMUST00000002198.4
      Conserved Domains (4) summary
      cd01800
      Location:716791
      SF3a120_C; Ubiquitin-like domain of Mammalian splicing factor SF3a_120
      smart00648
      Location:50103
      SWAP; Suppressor-of-White-APricot splicing regulator
      pfam01805
      Location:165215
      Surp; Surp module
      pfam12230
      Location:232470
      PRP21_like_P; Pre-mRNA splicing factor PRP21 like protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      4110354..4132541
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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