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    Frmd8 FERM domain containing 8 [ Mus musculus (house mouse) ]

    Gene ID: 67457, updated on 23-Jun-2021

    Summary

    Official Symbol
    Frmd8provided by MGI
    Official Full Name
    FERM domain containing 8provided by MGI
    Primary source
    MGI:MGI:1914707
    See related
    Ensembl:ENSMUSG00000024816
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    i; iTAP; AU018809; 1200004M23Rik; 2310035N23Rik; 4931429L16Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 47.8), small intestine adult (RPKM 26.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Frmd8 in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5901002..5925297, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5850974..5875269, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (5850974..5875208, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene Malat1-associated small cytoplasmic RNA Neighboring gene metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Neighboring gene nuclear paraspeckle assembly transcript 1 (non-protein coding) Neighboring gene FERM domain containing 8, opposite strand Neighboring gene solute carrier family 25, member 45 Neighboring gene tigger transposable element derived 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    FERM domain-containing protein 8
    Names
    iRhom tail-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026169.4NP_080445.1  FERM domain-containing protein 8

      See identical proteins and their annotated locations for NP_080445.1

      Status: VALIDATED

      Source sequence(s)
      AK083902
      Consensus CDS
      CCDS29481.1
      UniProtKB/Swiss-Prot
      Q3UFK8
      Related
      ENSMUSP00000025728.7, ENSMUST00000025728.13
      Conserved Domains (1) summary
      pfam00373
      Location:137273
      FERM_M; FERM central domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5901002..5925297 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531829.4XP_006531892.1  FERM domain-containing protein 8 isoform X2

      Conserved Domains (1) summary
      pfam00373
      Location:137273
      FERM_M; FERM central domain
    2. XM_006531828.3XP_006531891.1  FERM domain-containing protein 8 isoform X1

      See identical proteins and their annotated locations for XP_006531891.1

      UniProtKB/Swiss-Prot
      Q3UFK8
      Conserved Domains (1) summary
      pfam00373
      Location:137273
      FERM_M; FERM central domain
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