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    Ergic2 ERGIC and golgi 2 [ Mus musculus (house mouse) ]

    Gene ID: 67456, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ergic2provided by MGI
    Official Full Name
    ERGIC and golgi 2provided by MGI
    Primary source
    MGI:MGI:1914706
    See related
    Ensembl:ENSMUSG00000030304
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ptx1; AA408438; 1200009B18Rik; 4930572C01Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 11.8), testis adult (RPKM 11.7) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Ergic2 in Genome Data Viewer
    Location:
    6; 6 G3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (148080816..148113886, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (148179318..148212388, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (148127840..148160896, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene 15762 Neighboring gene fatty acyl CoA reductase 2, opposite strand 1 Neighboring gene fatty acyl CoA reductase 2 Neighboring gene RIKEN cDNA 4732416N19 gene Neighboring gene predicted gene, 52483 Neighboring gene transmembrane and tetratricopeptide repeat containing 1 Neighboring gene ribosomal protein S4-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    endoplasmic reticulum-Golgi intermediate compartment protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001286560.1NP_001273489.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate exon in the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC132613, AK016275, AK030045, AK162267
      UniProtKB/Swiss-Prot
      Q9CR89
      Conserved Domains (1) summary
      pfam07970
      Location:87249
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    2. NM_026168.4NP_080444.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform 1

      See identical proteins and their annotated locations for NP_080444.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC132613, AK016275, AK030045
      Consensus CDS
      CCDS20708.1
      UniProtKB/Swiss-Prot
      Q9CR89
      Related
      ENSMUSP00000120456.2, ENSMUST00000136008.8
      Conserved Domains (2) summary
      pfam07970
      Location:170332
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:1395
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      148080816..148113886 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030255556.1XP_030111416.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X2

      Conserved Domains (2) summary
      pfam07970
      Location:170322
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:1395
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
    2. XM_006507089.5XP_006507152.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X2

      See identical proteins and their annotated locations for XP_006507152.1

      Conserved Domains (2) summary
      pfam07970
      Location:170322
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:1395
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
    3. XM_030255558.2XP_030111418.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X6

      Conserved Domains (1) summary
      pfam07970
      Location:71233
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    4. XM_030255557.2XP_030111417.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X4

      Conserved Domains (1) summary
      pfam07970
      Location:87249
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    5. XM_030255560.2XP_030111420.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X7

      Conserved Domains (1) summary
      pfam07970
      Location:45207
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    6. XM_030255559.2XP_030111419.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X6

      Conserved Domains (1) summary
      pfam07970
      Location:71233
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    7. XM_030255561.2XP_030111421.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X8

      Related
      ENSMUSP00000145204.2, ENSMUST00000203268.2
      Conserved Domains (1) summary
      pfam07970
      Location:45197
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    8. XM_017321716.3XP_017177205.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q9CR89
      Conserved Domains (2) summary
      pfam07970
      Location:170332
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:1395
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
    9. XM_017321717.1XP_017177206.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X3

      UniProtKB/Swiss-Prot
      Q9CR89
      Conserved Domains (2) summary
      pfam07970
      Location:170280
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:1395
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
    10. XM_011241623.3XP_011239925.1  endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X5

      See identical proteins and their annotated locations for XP_011239925.1

      Conserved Domains (2) summary
      pfam07970
      Location:170270
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:1395
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

    RNA

    1. XR_001785162.2 RNA Sequence

    2. XR_378169.5 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_026355.3: Suppressed sequence

      Description
      NM_026355.3: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
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