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    Map1lc3b microtubule-associated protein 1 light chain 3 beta [ Mus musculus (house mouse) ]

    Gene ID: 67443, updated on 23-Oct-2018

    Summary

    Official Symbol
    Map1lc3bprovided by MGI
    Official Full Name
    microtubule-associated protein 1 light chain 3 betaprovided by MGI
    Primary source
    MGI:MGI:1914693
    See related
    Ensembl:ENSMUSG00000031812 Vega:OTTMUSG00000043032
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Atg8; LC3b; Map1lc3; MAP1A/MAP1B; 1010001C15Rik
    Expression
    Ubiquitous expression in kidney adult (RPKM 80.9), adrenal adult (RPKM 77.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Map1lc3b in Genome Data Viewer
    Location:
    8; 8 E1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (121590468..121598047)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (124114368..124121947)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA methionine 17 (anticodon CAT) Neighboring gene 40S ribosomal protein S23-like Neighboring gene zinc finger, CCHC domain containing 14 Neighboring gene predicted gene, 46065

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118046

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    tubulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    autophagosome maturation ISO
    Inferred from Sequence Orthology
    more info
     
    autophagy IDA
    Inferred from Direct Assay
    more info
    PubMed 
    autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    autophagy of mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    autophagy of mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to nitrogen starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to starvation ISO
    Inferred from Sequence Orthology
    more info
     
    macroautophagy ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mucus secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    autolysosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    autophagosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    autophagosome ISO
    Inferred from Sequence Orthology
    more info
     
    autophagosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    autophagosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    axon ISO
    Inferred from Sequence Orthology
    more info
     
    axoneme IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule associated complex ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    microtubule-associated proteins 1A/1B light chain 3B
    Names
    MAP1 light chain 3-like protein 2
    MAP1A/MAP1B light chain 3 B
    autophagy-related protein LC3 B
    autophagy-related ubiquitin-like modifier LC3 B

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364358.1NP_001351287.1  microtubule-associated proteins 1A/1B light chain 3B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC182458
      Conserved Domains (1) summary
      cd01611
      Location:7155
      GABARAP; Ubiquitin domain of GABA-receptor-associated protein
    2. NM_026160.5NP_080436.1  microtubule-associated proteins 1A/1B light chain 3B isoform 1

      See identical proteins and their annotated locations for NP_080436.1

      Status: VALIDATED

      Source sequence(s)
      AC182458
      Consensus CDS
      CCDS22726.1
      UniProtKB/Swiss-Prot
      Q9CQV6
      Related
      ENSMUSP00000034270.9, OTTMUSP00000063259, ENSMUST00000034270.16
      Conserved Domains (1) summary
      cd01611
      Location:7120
      GABARAP; Ubiquitin domain of GABA-receptor-associated protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      121590468..121598047
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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