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    Rps20 ribosomal protein S20 [ Mus musculus (house mouse) ]

    Gene ID: 67427, updated on 5-Sep-2021

    Summary

    Official Symbol
    Rps20provided by MGI
    Official Full Name
    ribosomal protein S20provided by MGI
    Primary source
    MGI:MGI:1914677
    See related
    Ensembl:ENSMUSG00000028234
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dsk; Dsk4; 4632426K06Rik
    Summary
    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Dec 2015]
    Expression
    Ubiquitous expression in liver E14 (RPKM 147.0), limb E14.5 (RPKM 117.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rps20 in Genome Data Viewer
    Location:
    4; 4 A1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (3831584..3835655, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (3831584..3835655, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (3761620..3762747, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene LYN proto-oncogene, Src family tyrosine kinase Neighboring gene high mobility group box 3 pseudogene Neighboring gene predicted gene, 22781 Neighboring gene predicted gene, 24016 Neighboring gene predicted gene, 32823 Neighboring gene predicted gene, 24125 Neighboring gene Moloney sarcoma oncogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102408

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables MDM2/MDM4 family protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin ligase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of signal transduction by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026147.6NP_080423.1  40S ribosomal protein S20

      See identical proteins and their annotated locations for NP_080423.1

      Status: REVIEWED

      Source sequence(s)
      AK136398, AL772401, AL807387, CJ041981
      Consensus CDS
      CCDS17940.1
      UniProtKB/Swiss-Prot
      P60867
      UniProtKB/TrEMBL
      Q5BLK2
      Related
      ENSMUSP00000120528.2, ENSMUST00000138502.2
      Conserved Domains (1) summary
      cl00314
      Location:16116
      Ribosomal_S10; Ribosomal protein S10p/S20e

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      3831584..3835655 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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