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    Srpr signal recognition particle receptor ('docking protein') [ Mus musculus (house mouse) ]

    Gene ID: 67398, updated on 16-Oct-2021

    Summary

    Official Symbol
    Srprprovided by MGI
    Official Full Name
    signal recognition particle receptor ('docking protein')provided by MGI
    Primary source
    MGI:MGI:1914648
    See related
    Ensembl:ENSMUSG00000032042
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Srpra; D11Mgi27; 1300011P19Rik
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 54.6), placenta adult (RPKM 40.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Srpr in Genome Data Viewer
    Location:
    9; 9 A4
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (35122499..35128299)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (35211203..35217003)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (35018788..35024588)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene toll-interleukin 1 receptor (TIR) domain-containing adaptor protein Neighboring gene predicted gene, 39318 Neighboring gene FAD-dependent oxidoreductase domain containing 1 Neighboring gene family with sequence similarity 118, member B Neighboring gene RNA pseudouridylate synthase domain containing 4 Neighboring gene RIKEN cDNA 4933422A05 gene Neighboring gene ribosomal protein L36 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables signal recognition particle binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein targeting IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein targeting to ER IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    part_of signal recognition particle receptor complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    signal recognition particle receptor subunit alpha
    Names
    DP-alpha
    SR-alpha
    docking protein alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026130.1NP_080406.1  signal recognition particle receptor subunit alpha

      See identical proteins and their annotated locations for NP_080406.1

      Status: PROVISIONAL

      Source sequence(s)
      AK004967
      Consensus CDS
      CCDS22959.1
      UniProtKB/Swiss-Prot
      Q9DBG7
      Related
      ENSMUSP00000034541.6, ENSMUST00000034541.12
      Conserved Domains (4) summary
      smart00963
      Location:322395
      SRP54_N; SRP54-type protein, helical bundle domain
      cd03115
      Location:417613
      SRP; The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The ...
      TIGR00064
      Location:334633
      ftsY; signal recognition particle-docking protein FtsY
      pfam04086
      Location:27296
      SRP-alpha_N; Signal recognition particle, alpha subunit, N-terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      35122499..35128299
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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