Format

Send to:

Choose Destination
    • Showing Current items.

    Carnmt1 carnosine N-methyltransferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 67383, updated on 23-Jun-2021

    Summary

    Official Symbol
    Carnmt1provided by MGI
    Official Full Name
    carnosine N-methyltransferase 1provided by MGI
    Primary source
    MGI:MGI:1914633
    See related
    Ensembl:ENSMUSG00000024726
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2410127L17Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 5.9), liver E14 (RPKM 5.1) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Carnmt1 in Genome Data Viewer
    Location:
    19 B; 19
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (18648099..18684565)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (18670759..18707201)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (18745270..18779282)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene osteoclast stimulating factor 1 Neighboring gene nicotinamide riboside kinase 1 Neighboring gene RIKEN cDNA D030056L22 gene Neighboring gene predicted gene, 23238 Neighboring gene transient receptor potential cation channel, subfamily M, member 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables S-adenosylmethionine-dependent methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables carnosine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables carnosine N-methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in carnosine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in carnosine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    carnosine N-methyltransferase
    Names
    UPF0586 protein C9orf41 homolog
    NP_001363980.1
    NP_001363981.1
    NP_001363982.1
    NP_001363983.1
    NP_001363984.1
    NP_080396.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001377051.1NP_001363980.1  carnosine N-methyltransferase isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC134906
      Conserved Domains (1) summary
      pfam07942
      Location:90355
      N2227; N2227-like protein
    2. NM_001377052.1NP_001363981.1  carnosine N-methyltransferase isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC134906
      Conserved Domains (1) summary
      pfam07942
      Location:83348
      N2227; N2227-like protein
    3. NM_001377053.1NP_001363982.1  carnosine N-methyltransferase isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC134906
      Conserved Domains (1) summary
      pfam07942
      Location:135333
      N2227; N2227-like protein
    4. NM_001377054.1NP_001363983.1  carnosine N-methyltransferase isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC134906
      Conserved Domains (1) summary
      pfam07942
      Location:90288
      N2227; N2227-like protein
    5. NM_001377055.1NP_001363984.1  carnosine N-methyltransferase isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC134906
      Conserved Domains (1) summary
      pfam07942
      Location:83281
      N2227; N2227-like protein
    6. NM_026120.5NP_080396.2  carnosine N-methyltransferase isoform 1

      See identical proteins and their annotated locations for NP_080396.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC134906
      Consensus CDS
      CCDS29689.1
      UniProtKB/Swiss-Prot
      Q80UY1
      Related
      ENSMUSP00000025632.10, ENSMUST00000025632.11
      Conserved Domains (1) summary
      pfam07942
      Location:135400
      N2227; N2227-like protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      18648099..18684565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_004940170.1 RNA Sequence

    2. XR_004940171.1 RNA Sequence

    Support Center