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    Med4 mediator complex subunit 4 [ Mus musculus (house mouse) ]

    Gene ID: 67381, updated on 2-Oct-2018

    Summary

    Official Symbol
    Med4provided by MGI
    Official Full Name
    mediator complex subunit 4provided by MGI
    Primary source
    MGI:MGI:1914631
    See related
    Ensembl:ENSMUSG00000022109
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Vdirp; Vdrip; DRIP36; TRAP36; HSPC126; 2410046H15Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 28.4), CNS E14 (RPKM 19.9) and 27 other tissues See more
    Orthologs

    Genomic context

    See Med4 in Genome Data Viewer
    Location:
    14; 14 D3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (73510049..73518545)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (73909856..73918352)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 35450 Neighboring gene predicted gene 4266 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 15 Neighboring gene predicted gene, 41209 Neighboring gene succinate-Coenzyme A ligase, ADP-forming, beta subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    thyroid hormone receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription coregulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    androgen receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular steroid hormone receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    transcription initiation from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mediator complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 4
    Names
    mediator of RNA polymerase II transcription, subunit 4 homolog
    p36 TRAP/SMCC/PC2 subunit
    vitamin D receptor interacting protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026119.3NP_080395.1  mediator of RNA polymerase II transcription subunit 4

      See identical proteins and their annotated locations for NP_080395.1

      Status: PROVISIONAL

      Source sequence(s)
      AC113198
      Consensus CDS
      CCDS49538.1
      UniProtKB/Swiss-Prot
      Q9CQA5
      Related
      ENSMUSP00000022705.5, ENSMUST00000022705.6
      Conserved Domains (1) summary
      pfam10018
      Location:64202
      Med4; Vitamin-D-receptor interacting Mediator subunit 4

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      73510049..73518545
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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