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    Gtf3c6 general transcription factor IIIC, polypeptide 6, alpha [ Mus musculus (house mouse) ]

    Gene ID: 67371, updated on 2-Nov-2024

    Summary

    Official Symbol
    Gtf3c6provided by MGI
    Official Full Name
    general transcription factor IIIC, polypeptide 6, alphaprovided by MGI
    Primary source
    MGI:MGI:1914621
    See related
    Ensembl:ENSMUSG00000019837 AllianceGenome:MGI:1914621
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2410016F19Rik
    Summary
    Predicted to contribute to DNA binding activity. Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nuclear body. Predicted to be part of transcription factor TFIIIC complex. Orthologous to human GTF3C6 (general transcription factor IIIC subunit 6). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 16.4), CNS E14 (RPKM 12.0) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Gtf3c6 in Genome Data Viewer
    Location:
    10 B1; 10 21.79 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (40123697..40133708, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (40247701..40257712, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31992 Neighboring gene STARR-seq mESC enhancer starr_26412 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:39952398-39952599 Neighboring gene ribosome production factor 2 homolog Neighboring gene STARR-positive B cell enhancer ABC_E10600 Neighboring gene STARR-seq mESC enhancer starr_26413 Neighboring gene small nucleolar RNA, C/D box 3A Neighboring gene STARR-positive B cell enhancer ABC_E2319 Neighboring gene S-adenosylmethionine decarboxylase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transcription by RNA polymerase III IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transcription by RNA polymerase III ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription factor TFIIIC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of transcription factor TFIIIC complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    general transcription factor 3C polypeptide 6
    Names
    TFIIIC 35 kDa subunit
    TFIIIC35
    transcription factor IIIC 35 kDa subunit
    transcription factor IIIC subunit 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359491.1NP_001346420.1  general transcription factor 3C polypeptide 6 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC131684, AC164625, AI430887, AK005261, BY110346
      Consensus CDS
      CCDS87991.1
      UniProtKB/TrEMBL
      Q9DB36
      Related
      ENSMUSP00000019982.9, ENSMUST00000019982.9
      Conserved Domains (1) summary
      pfam10419
      Location:5285
      TFIIIC_sub6; TFIIIC subunit
    2. NM_001359492.1NP_001346421.1  general transcription factor 3C polypeptide 6 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC131684, AC164625, AI430887, AK007816, BU695477, BY110346
      Conserved Domains (1) summary
      pfam10419
      Location:122
      TFIIIC_sub6; TFIIIC subunit
    3. NM_001359493.1NP_001346422.1  general transcription factor 3C polypeptide 6 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC131684, AC164625, AI430887, AK007816, BY253152
      Conserved Domains (1) summary
      pfam10419
      Location:122
      TFIIIC_sub6; TFIIIC subunit
    4. NM_026113.5NP_080389.2  general transcription factor 3C polypeptide 6 isoform 2

      See identical proteins and their annotated locations for NP_080389.2

      Status: VALIDATED

      Source sequence(s)
      AC131684, AC164625, AI430887, AK007816, BY110346
      Consensus CDS
      CCDS23794.1
      UniProtKB/Swiss-Prot
      Q8R2T6, Q9D8P7
      Related
      ENSMUSP00000151091.2, ENSMUST00000217537.2
      Conserved Domains (1) summary
      pfam10419
      Location:5184
      TFIIIC_sub6; TFIIIC subunit

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      40123697..40133708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)