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    Paxbp1 PAX3 and PAX7 binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 67367, updated on 31-Jan-2019

    Summary

    Official Symbol
    Paxbp1provided by MGI
    Official Full Name
    PAX3 and PAX7 binding protein 1provided by MGI
    Primary source
    MGI:MGI:1914617
    See related
    Ensembl:ENSMUSG00000022974
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gcfc; Gcfc1; C21orf66; Pax3/7bp; 1810007M14Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 28.4), CNS E14 (RPKM 26.4) and 25 other tissues See more
    Orthologs

    Genomic context

    See Paxbp1 in Genome Data Viewer
    Location:
    16; 16 C3.3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (91014037..91044610, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (91014282..91044624, complement)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene cilia and flagella associate protien 298 Neighboring gene synaptojanin 1 Neighboring gene predicted gene, 41491 Neighboring gene RIKEN cDNA 4930404I05 gene Neighboring gene RIKEN cDNA 4932438H23 gene Neighboring gene H3 histone, family 3A, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II proximal promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    PAX3- and PAX7-binding protein 1
    Names
    GC-rich sequence DNA-binding factor 1
    GC-rich sequence DNA-binding factor homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026110.2NP_080386.3  PAX3- and PAX7-binding protein 1

      See identical proteins and their annotated locations for NP_080386.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the functional protein.
      Source sequence(s)
      AC141885
      Consensus CDS
      CCDS49908.1
      UniProtKB/Swiss-Prot
      P58501
      Related
      ENSMUSP00000113835.1, ENSMUST00000118522.7
      Conserved Domains (1) summary
      pfam07842
      Location:597808
      GCFC; GC-rich sequence DNA-binding factor-like protein

    RNA

    1. NR_152264.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 3' region compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC141885

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      91014037..91044610 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_384945.3 RNA Sequence

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