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    Stk35 serine/threonine kinase 35 [ Mus musculus (house mouse) ]

    Gene ID: 67333, updated on 5-Sep-2021

    Summary

    Official Symbol
    Stk35provided by MGI
    Official Full Name
    serine/threonine kinase 35provided by MGI
    Primary source
    MGI:MGI:1914583
    See related
    Ensembl:ENSMUSG00000037885
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CLI; CLIK1; Stk35l1; 1700054C12Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 34.5), ovary adult (RPKM 13.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Stk35 in Genome Data Viewer
    Location:
    2; 2 F1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (129642437..129674207)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (129800517..129832287)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (129626253..129658023)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene prodynorphin Neighboring gene peptidylprolyl isomerase A (Ppia) pseudogene 2_1620.1 Neighboring gene serine/threonine kinase 35, opposite strand 1 Neighboring gene predicted gene, 39933 Neighboring gene transglutaminase 3, E polypeptide Neighboring gene predicted gene, 52561

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein kinase 35
    Names
    CLP-36 interacting kinase
    serine/threonine-protein kinase 35 L1
    NP_001033724.2
    NP_899085.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038635.2NP_001033724.2  serine/threonine-protein kinase 35 isoform b

      Status: VALIDATED

      Source sequence(s)
      AI431080, AK085193, AL808137
      Consensus CDS
      CCDS16731.2
      UniProtKB/TrEMBL
      E9PXA2
      Related
      ENSMUSP00000132862.3, ENSMUST00000166282.3
      Conserved Domains (1) summary
      cl21453
      Location:206304
      PKc_like; Protein Kinases, catalytic domain
    2. NM_183262.3NP_899085.3  serine/threonine-protein kinase 35 isoform a

      See identical proteins and their annotated locations for NP_899085.3

      Status: VALIDATED

      Source sequence(s)
      AI431080, AK006778, AK085193, AL808137, BC047277
      Consensus CDS
      CCDS16732.2
      UniProtKB/Swiss-Prot
      Q80ZW0
      Related
      ENSMUSP00000126541.3, ENSMUST00000165413.9
      Conserved Domains (2) summary
      smart00220
      Location:207528
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd13977
      Location:206534
      STKc_PDIK1L; Catalytic domain of the Serine/Threonine kinase, PDLIM1 interacting kinase 1 like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      129642437..129674207
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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