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    Gprasp1 G protein-coupled receptor associated sorting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 67298, updated on 3-May-2022

    Summary

    Official Symbol
    Gprasp1provided by MGI
    Official Full Name
    G protein-coupled receptor associated sorting protein 1provided by MGI
    Primary source
    MGI:MGI:1917418
    See related
    Ensembl:ENSMUSG00000043384 AllianceGenome:MGI:1917418
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GASP; GASP1; C87852; 2210415K24Rik; 3110031O14Rik
    Summary
    Predicted to be involved in G protein-coupled receptor catabolic process and endosome to lysosome transport. Predicted to be located in cytosol and nucleus. Is expressed in brain. Orthologous to human GPRASP1 (G protein-coupled receptor associated sorting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in CNS E18 (RPKM 73.7), CNS E14 (RPKM 50.7) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gprasp1 in Genome Data Viewer
    Location:
    X; X F1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (134643441..134704217)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (135742692..135803468)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (132277231..132338007)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene t-complex 11 family, X-linked 2 Neighboring gene thymosin beta 15a Neighboring gene microRNA 7646 Neighboring gene armadillo repeat containing, X-linked 5 Neighboring gene RAB18, member RAS oncogene family pseudogene Neighboring gene microRNA 1970 Neighboring gene G protein-coupled receptor associated sorting protein 2 Neighboring gene basic helix-loop-helix domain containing, class B9 Neighboring gene predicted gene, 31214

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC100209

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    G-protein coupled receptor-associated sorting protein 1
    Names
    GASP-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004359.2NP_001004359.1  G-protein coupled receptor-associated sorting protein 1

      See identical proteins and their annotated locations for NP_001004359.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AB093241, BB619497, BC027187, BC070413, BY099746
      Consensus CDS
      CCDS30409.1
      UniProtKB/Swiss-Prot
      Q5U4C1
      Conserved Domains (1) summary
      pfam04826
      Location:11171303
      Arm_2; Armadillo-like
    2. NM_001005385.1NP_001005385.1  G-protein coupled receptor-associated sorting protein 1

      See identical proteins and their annotated locations for NP_001005385.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AB093241, AK083192, BB619497, BC027187, BC070413
      Consensus CDS
      CCDS30409.1
      UniProtKB/Swiss-Prot
      Q5U4C1
      Related
      ENSMUSP00000108770.2, ENSMUST00000113145.8
      Conserved Domains (1) summary
      pfam04826
      Location:11171303
      Arm_2; Armadillo-like
    3. NM_026081.5NP_080357.4  G-protein coupled receptor-associated sorting protein 1

      See identical proteins and their annotated locations for NP_080357.4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      BB619497, BC058970, BC070413
      Consensus CDS
      CCDS30409.1
      UniProtKB/Swiss-Prot
      Q5U4C1
      UniProtKB/TrEMBL
      Q6PD32
      Related
      ENSMUSP00000108769.2, ENSMUST00000113144.8
      Conserved Domains (1) summary
      pfam04826
      Location:11171303
      Arm_2; Armadillo-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      134643441..134704217
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)