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    Srek1ip1 splicing regulatory glutamine/lysine-rich protein 1interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 67288, updated on 18-Sep-2024

    Summary

    Official Symbol
    Srek1ip1provided by MGI
    Official Full Name
    splicing regulatory glutamine/lysine-rich protein 1interacting protein 1provided by MGI
    Primary source
    MGI:MGI:1914538
    See related
    Ensembl:ENSMUSG00000021716 AllianceGenome:MGI:1914538
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sfrs12ip1; Srsf12ip1; 3110031B13Rik
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to act upstream of or within RNA splicing and mRNA processing. Is expressed in brain; central nervous system ganglion; and sensory organ. Orthologous to human SREK1IP1 (SREK1 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 7.1), CNS E11.5 (RPKM 6.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Srek1ip1 in Genome Data Viewer
    Location:
    13 D1; 13 56.84 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (104953696..104975805)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (104817170..104838676)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 6 Neighboring gene STARR-seq mESC enhancer starr_35537 Neighboring gene predicted gene 8680 Neighboring gene STARR-seq mESC enhancer starr_35538 Neighboring gene STARR-seq mESC enhancer starr_35540 Neighboring gene predicted gene, 53810 Neighboring gene CWC27 spliceosome-associated protein Neighboring gene STARR-positive B cell enhancer mm9_chr13:105580054-105580355 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:105607138-105607403 Neighboring gene STARR-seq mESC enhancer starr_35542 Neighboring gene shisa like 2B Neighboring gene STARR-seq mESC enhancer starr_35543 Neighboring gene STARR-seq mESC enhancer starr_35545 Neighboring gene predicted gene, 41048 Neighboring gene H3 histone, family 3 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    protein SREK1IP1
    Names
    SFRS12-interacting protein 1
    SREK1-interacting protein 1
    protein SFRS12IP1
    serine/arginine-rich splicing factor 12, interacting protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001409332.1NP_001396261.1  protein SREK1IP1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC137691
    2. NM_001409333.1NP_001396262.1  protein SREK1IP1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC137691
    3. NM_026075.4NP_080351.2  protein SREK1IP1 isoform 1

      See identical proteins and their annotated locations for NP_080351.2

      Status: VALIDATED

      Source sequence(s)
      AC137691
      Consensus CDS
      CCDS26753.1
      UniProtKB/Swiss-Prot
      Q05CD6, Q4V9W2, Q8CGG6, Q9CRM9, Q9CRR4, Q9CXR0
      Related
      ENSMUSP00000022230.9, ENSMUST00000022230.15
      Conserved Domains (1) summary
      pfam13917
      Location:930
      zf-CCHC_3; Zinc knuckle

    RNA

    1. NR_135272.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC137691

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      104953696..104975805
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)