Format

Send to:

Choose Destination
    • Showing Current items.

    Lsm1 LSM1 homolog, mRNA degradation associated [ Mus musculus (house mouse) ]

    Gene ID: 67207, updated on 23-Jun-2021

    Summary

    Official Symbol
    Lsm1provided by MGI
    Official Full Name
    LSM1 homolog, mRNA degradation associatedprovided by MGI
    Primary source
    MGI:MGI:1914457
    See related
    Ensembl:ENSMUSG00000037296
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CASM; 2810025O06Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 6.5), CNS E11.5 (RPKM 6.1) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Lsm1 in Genome Data Viewer
    Location:
    8; 8 A2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (26275326..26294003)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (25785318..25803975)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (26896063..26914447)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 17484 Neighboring gene BCL2-associated athanogene 4 Neighboring gene electron transferring flavoprotein, alpha polypeptide pseudogene Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene Star 5' regulatory region Neighboring gene steroidogenic acute regulatory protein Neighboring gene ASH2 like histone lysine methyltransferase complex subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA cap binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables pre-mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of Lsm1-7-Pat1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in P-body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axon ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    part_of messenger ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    U6 snRNA-associated Sm-like protein LSm1
    Names
    LSM1 homolog, U6 small nuclear RNA associated
    U6 small nuclear RNA associated

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026032.1NP_080308.1  U6 snRNA-associated Sm-like protein LSm1

      See identical proteins and their annotated locations for NP_080308.1

      Status: VALIDATED

      Source sequence(s)
      AK041290
      Consensus CDS
      CCDS22202.1
      UniProtKB/Swiss-Prot
      Q8VC85
      UniProtKB/TrEMBL
      Q544C9
      Related
      ENSMUSP00000041022.7, ENSMUST00000038421.8
      Conserved Domains (2) summary
      PRK10788
      Location:64131
      PRK10788; periplasmic folding chaperone; Provisional
      cd01728
      Location:477
      LSm1; Like-Sm protein 1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      26275326..26294003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242156.4XP_011240458.1  U6 snRNA-associated Sm-like protein LSm1 isoform X1

      Conserved Domains (1) summary
      cd01728
      Location:477
      LSm1; Like-Sm protein 1
    Support Center