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    Rplp2 ribosomal protein, large P2 [ Mus musculus (house mouse) ]

    Gene ID: 67186, updated on 9-Sep-2018

    Summary

    Official Symbol
    Rplp2provided by MGI
    Official Full Name
    ribosomal protein, large P2provided by MGI
    Primary source
    MGI:MGI:1914436
    See related
    Ensembl:ENSMUSG00000025508 Vega:OTTMUSG00000024569
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2700049I22Rik
    Expression
    Ubiquitous expression in liver E14 (RPKM 465.0), bladder adult (RPKM 400.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rplp2 in Genome Data Viewer
    Location:
    7; 7 F5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (141447464..141451350)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (148633549..148637241)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 (mitochondrial carrier, glutamate), member 22 Neighboring gene p53 induced death domain protein 1 Neighboring gene small nucleolar RNA, H/ACA box 52 Neighboring gene patatin-like phospholipase domain containing 2 Neighboring gene calcium release activated channel regulator 2B Neighboring gene predicted gene 10575

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    translational elongation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     
    ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    60S acidic ribosomal protein P2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360657.1NP_001347586.1  60S acidic ribosomal protein P2 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AC102547
      Conserved Domains (1) summary
      cd05833
      Location:166
      Ribosomal_P2; Ribosomal protein P2. This subfamily represents the eukaryotic large ribosomal protein P2. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P2 is located in the L12 stalk, with proteins ...
    2. NM_001360658.1NP_001347587.1  60S acidic ribosomal protein P2 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice junction in the 3' end compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a.
      Source sequence(s)
      AC102547
      Conserved Domains (1) summary
      cd05833
      Location:166
      Ribosomal_P2; Ribosomal protein P2. This subfamily represents the eukaryotic large ribosomal protein P2. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P2 is located in the L12 stalk, with proteins ...
    3. NM_026020.7NP_080296.3  60S acidic ribosomal protein P2 isoform a

      See identical proteins and their annotated locations for NP_080296.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AC102547
      Consensus CDS
      CCDS40187.1
      UniProtKB/Swiss-Prot
      P99027
      Related
      ENSMUSP00000081474.4, OTTMUSP00000029428, ENSMUST00000084434.10
      Conserved Domains (1) summary
      cd05833
      Location:166
      Ribosomal_P2; Ribosomal protein P2. This subfamily represents the eukaryotic large ribosomal protein P2. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P2 is located in the L12 stalk, with proteins ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      141447464..141451350
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006536229.1XP_006536292.1  60S acidic ribosomal protein P2 isoform X1

      UniProtKB/Swiss-Prot
      P99027
      Conserved Domains (1) summary
      cd05833
      Location:166
      Ribosomal_P2; Ribosomal protein P2. This subfamily represents the eukaryotic large ribosomal protein P2. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P2 is located in the L12 stalk, with proteins ...
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