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    Arl8b ADP-ribosylation factor-like 8B [ Mus musculus (house mouse) ]

    Gene ID: 67166, updated on 8-Jul-2021

    Summary

    Official Symbol
    Arl8bprovided by MGI
    Official Full Name
    ADP-ribosylation factor-like 8Bprovided by MGI
    Primary source
    MGI:MGI:1914416
    See related
    Ensembl:ENSMUSG00000030105
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arl; gie1; Arl10c; 2610313E07Rik; 3100002J04Rik
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 29.8), cortex adult (RPKM 29.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Arl8b in Genome Data Viewer
    Location:
    6; 6 E2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (108760020..108800684)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (108783059..108823723)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (108733053..108773717)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 0610040F04 gene Neighboring gene basic helix-loop-helix family, member e40 Neighboring gene predicted gene, 35359 Neighboring gene predicted gene, 51409 Neighboring gene predicted gene, 35417 Neighboring gene ER degradation enhancer, mannosidase alpha-like 1 Neighboring gene predicted pseudogene 6749

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables alpha-tubulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables beta-tubulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in anterograde axonal transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in antigen processing and presentation following phagocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in antigen processing and presentation of polysaccharide antigen via MHC class II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in autophagosome-lysosome fusion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in calcium ion regulated lysosome exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome segregation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within endosomal transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in endosome to lysosome transport of low-density lipoprotein particle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in late endosome to lysosome transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in late endosome to lysosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lysosome localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in natural killer cell mediated cytotoxicity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phagosome-lysosome fusion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in plasma membrane repair ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in viral exocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in viral exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytolytic granule membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle midzone ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in vacuolar membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    ADP-ribosylation factor-like protein 8B
    Names
    ADP-ribosylation factor-like 10C
    ADP-ribosylation factor-like protein 10C
    novel small G protein indispensable for equal chromosome segregation 1
    small G protein indispensable for equal chromosome segregation 1
    NP_080287.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026011.3NP_080287.1  ADP-ribosylation factor-like protein 8B

      See identical proteins and their annotated locations for NP_080287.1

      Status: VALIDATED

      Source sequence(s)
      AC132443, AK144177, BY261755
      Consensus CDS
      CCDS39586.1
      UniProtKB/Swiss-Prot
      Q9CQW2
      Related
      ENSMUSP00000032196.7, ENSMUST00000032196.9
      Conserved Domains (1) summary
      cd04159
      Location:22180
      Arl10_like; Arf-like 9 (Arl9) and 10 (Arl10) GTPases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      108760020..108800684
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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