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    Ramac RNA guanine-7 methyltransferase activating subunit [ Mus musculus (house mouse) ]

    Gene ID: 67148, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ramacprovided by MGI
    Official Full Name
    RNA guanine-7 methyltransferase activating subunitprovided by MGI
    Primary source
    MGI:MGI:1914398
    See related
    Ensembl:ENSMUSG00000038646
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RAM; Ramm; Fam103; Rammet; Fam103a1; 2410047I02Rik; 2610204K14Rik
    Expression
    Ubiquitous expression in bladder adult (RPKM 29.5), CNS E18 (RPKM 25.4) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Ramac in Genome Data Viewer
    Location:
    7; 7 D3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (81412701..81419238)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (81762953..81769490)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (88907839..88914376)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42400 Neighboring gene G2/M-phase specific E3 ubiquitin ligase pseudogene Neighboring gene RIKEN cDNA 3110040N11 gene Neighboring gene BTB (POZ) domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables enzyme activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in 7-methylguanosine mRNA capping ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in RNA 5'-cap (guanine-N7)-methylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in methylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of mRNA cap binding complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mRNA cap binding complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mRNA cap methyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mRNA cap methyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    RNA guanine-N7 methyltransferase activating subunit
    Names
    RNMT actvating mRNA cap methylating subunit
    RNMT-activating mRNA cap methylating subunit
    RNMT-activating mRNA cap methyltransferase subunit
    RNMT-activating mini protein
    family with sequence similarity 103, member A1
    protein FAM103A1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025997.2NP_080273.1  RNA guanine-N7 methyltransferase activating subunit

      See identical proteins and their annotated locations for NP_080273.1

      Status: PROVISIONAL

      Source sequence(s)
      AC102077, AC130538
      Consensus CDS
      CCDS21406.1
      UniProtKB/Swiss-Prot
      Q9CQY2
      Related
      ENSMUSP00000039065.5, ENSMUST00000042166.11
      Conserved Domains (1) summary
      pfam15320
      Location:1087
      RAM; mRNA cap methylation, RNMT-activating mini protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      81412701..81419238
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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