Format

Send to:

Choose Destination
    • Showing Current items.

    Lrrc40 leucine rich repeat containing 40 [ Mus musculus (house mouse) ]

    Gene ID: 67144, updated on 8-Aug-2021

    Summary

    Official Symbol
    Lrrc40provided by MGI
    Official Full Name
    leucine rich repeat containing 40provided by MGI
    Primary source
    MGI:MGI:1914394
    See related
    Ensembl:ENSMUSG00000063052
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI837674; 2610040E16Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 11.4), placenta adult (RPKM 9.4) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Lrrc40 in Genome Data Viewer
    Location:
    3; 3 H4
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (157742319..157772727)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (158036682..158067090)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (157699667..157731442)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 13c Neighboring gene serine and arginine-rich splicing factor 11 Neighboring gene leucine rich repeat containing 7 Neighboring gene crumbs homolog 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein serine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    leucine-rich repeat-containing protein 40

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001289524.1NP_001276453.1  leucine-rich repeat-containing protein 40 isoform b

      See identical proteins and their annotated locations for NP_001276453.1

      Status: VALIDATED

      Source sequence(s)
      AC145301, AK034978, AW492724, CJ072347
      UniProtKB/Swiss-Prot
      Q9CRC8
      UniProtKB/TrEMBL
      Q78KN5
      Conserved Domains (4) summary
      cd00116
      Location:25150
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00031
      Location:349360
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:2748
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:47106
      LRR_8; Leucine rich repeat
    2. NM_001289525.1NP_001276454.1  leucine-rich repeat-containing protein 40 isoform b

      See identical proteins and their annotated locations for NP_001276454.1

      Status: VALIDATED

      Source sequence(s)
      AK152244, AW492724, CJ072347
      UniProtKB/TrEMBL
      Q78KN5
      Conserved Domains (4) summary
      cd00116
      Location:25150
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00031
      Location:349360
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:2748
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:47106
      LRR_8; Leucine rich repeat
    3. NM_001359763.1NP_001346692.1  leucine-rich repeat-containing protein 40 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC145301, AW492724
      Conserved Domains (3) summary
      sd00031
      Location:444455
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:729
      LRR_RI; leucine-rich repeat [structural motif]
      cl26793
      Location:20454
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    4. NM_024194.6NP_077156.2  leucine-rich repeat-containing protein 40 isoform a

      See identical proteins and their annotated locations for NP_077156.2

      Status: VALIDATED

      Source sequence(s)
      AK034978, AW492724, CJ072347
      Consensus CDS
      CCDS17935.1
      UniProtKB/Swiss-Prot
      Q9CRC8
      UniProtKB/TrEMBL
      A0A0R4J0W6
      Related
      ENSMUSP00000071956.4, ENSMUST00000072080.10
      Conserved Domains (4) summary
      cd00116
      Location:101368
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00031
      Location:567578
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:84106
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:129186
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      157742319..157772727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252769.1XP_030108629.1  leucine-rich repeat-containing protein 40 isoform X1

      Conserved Domains (4) summary
      PRK15370
      Location:2273
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      COG4886
      Location:176334
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:256278
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:425
      LRR_RI; leucine-rich repeat [structural motif]
    Support Center