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    Kbtbd4 kelch repeat and BTB (POZ) domain containing 4 [ Mus musculus (house mouse) ]

    Gene ID: 67136, updated on 31-Jan-2019

    Summary

    Official Symbol
    Kbtbd4provided by MGI
    Official Full Name
    kelch repeat and BTB (POZ) domain containing 4provided by MGI
    Primary source
    MGI:MGI:1914386
    See related
    Ensembl:ENSMUSG00000005505
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2510026C23Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 12.4), whole brain E14.5 (RPKM 11.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Kbtbd4 in Genome Data Viewer
    Location:
    2; 2 E1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (90904740..90910561)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (90744943..90750717)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32514 Neighboring gene NADH:ubiquinone oxidoreductase core subunit S3 Neighboring gene protein tyrosine phosphatase, mitochondrial 1 Neighboring gene CUGBP, Elav-like family member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    kelch repeat and BTB domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001311116.1NP_001298045.1  kelch repeat and BTB domain-containing protein 4 isoform 1

      See identical proteins and their annotated locations for NP_001298045.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      BC025103, BY787748
      Consensus CDS
      CCDS79820.1
      UniProtKB/Swiss-Prot
      Q8R179
      Related
      ENSMUSP00000107089.1, ENSMUST00000111464.7
      Conserved Domains (6) summary
      smart00225
      Location:62156
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cd14733
      Location:158216
      BACK_like; BTB-And-C-terminal-Kelch (BACK) domain and similar domains
      TIGR03548
      Location:370527
      mutarot_permut; cyclically-permuted mutarotase family protein
      sd00038
      Location:295330
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:55154
      BTB; BTB/POZ domain
      pfam07646
      Location:294330
      Kelch_2; Kelch motif
    2. NM_001361372.1NP_001348301.1  kelch repeat and BTB domain-containing protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL672241
      Conserved Domains (4) summary
      cd14733
      Location:142200
      BACK_like; BTB-And-C-terminal-Kelch (BACK) domain and similar domains
      sd00038
      Location:279314
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:35138
      BTB; BTB/POZ domain
      cl28614
      Location:47479
      BTB; Broad-Complex, Tramtrack and Bric a brac
    3. NM_025991.4NP_080267.1  kelch repeat and BTB domain-containing protein 4 isoform 2

      See identical proteins and their annotated locations for NP_080267.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate exon in the 5' UTR which results in the use of a downstream AUG compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AL672241
      Consensus CDS
      CCDS16419.1
      UniProtKB/Swiss-Prot
      Q8R179
      Related
      ENSMUSP00000088179.3, ENSMUST00000090682.3
      Conserved Domains (4) summary
      cd14733
      Location:142200
      BACK_like; BTB-And-C-terminal-Kelch (BACK) domain and similar domains
      sd00038
      Location:279314
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:35138
      BTB; BTB/POZ domain
      cl28614
      Location:47479
      BTB; Broad-Complex, Tramtrack and Bric a brac

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      90904740..90910561
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319215.1XP_017174704.1  kelch repeat and BTB domain-containing protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q8R179
      Conserved Domains (4) summary
      cd14733
      Location:142200
      BACK_like; BTB-And-C-terminal-Kelch (BACK) domain and similar domains
      sd00038
      Location:279314
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:35138
      BTB; BTB/POZ domain
      cl28614
      Location:47479
      BTB; Broad-Complex, Tramtrack and Bric a brac
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