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    Rpp14 ribonuclease P 14 subunit [ Mus musculus (house mouse) ]

    Gene ID: 67053, updated on 2-Nov-2024

    Summary

    Official Symbol
    Rpp14provided by MGI
    Official Full Name
    ribonuclease P 14 subunitprovided by MGI
    Primary source
    MGI:MGI:1914303
    See related
    Ensembl:ENSMUSG00000023156 AllianceGenome:MGI:1914303
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610511E03Rik
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be part of multimeric ribonuclease P complex. Predicted to be active in nucleolus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human RPP14 (ribonuclease P/MRP subunit p14). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in bladder adult (RPKM 6.3), placenta adult (RPKM 6.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rpp14 in Genome Data Viewer
    Location:
    14 A1; 14 4.7 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (14377927..14389460, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (8080313..8091846)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_35863 Neighboring gene pyruvate dehydrogenase (lipoamide) beta Neighboring gene PX domain containing serine/threonine kinase Neighboring gene STARR-positive B cell enhancer mm9_chr14:8946918-8947218 Neighboring gene ribosomal protein L13 pseudogene Neighboring gene hydroxyacyl-thioester dehydratase type 2 Neighboring gene STARR-seq mESC enhancer starr_35858 Neighboring gene STARR-seq mESC enhancer starr_35854 Neighboring gene abhydrolase domain containing 6 Neighboring gene STARR-positive B cell enhancer ABC_E9890 Neighboring gene predicted gene, 30244 Neighboring gene deoxyribonuclease 1-like 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ribonuclease P RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribonuclease P RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ribonuclease P RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    contributes_to ribonuclease P activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ribonuclease P activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in tRNA 5'-leader removal IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in tRNA 5'-leader removal ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA 5'-leader removal ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of multimeric ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of multimeric ribonuclease P complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of multimeric ribonuclease P complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    ribonuclease P protein subunit p14
    Names
    ribonuclease P 14kDa subunit
    NP_080214.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025938.4NP_080214.1  ribonuclease P protein subunit p14

      See identical proteins and their annotated locations for NP_080214.1

      Status: VALIDATED

      Source sequence(s)
      AK016631, BB726979, CF896465
      Consensus CDS
      CCDS26809.1
      UniProtKB/Swiss-Prot
      Q9CQH8
      Related
      ENSMUSP00000023924.4, ENSMUST00000023924.4
      Conserved Domains (1) summary
      pfam01900
      Location:33106
      RNase_P_Rpp14; Rpp14/Pop5 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      14377927..14389460 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)