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    Rpl11 ribosomal protein L11 [ Mus musculus (house mouse) ]

    Gene ID: 67025, updated on 22-Aug-2021

    Summary

    Official Symbol
    Rpl11provided by MGI
    Official Full Name
    ribosomal protein L11provided by MGI
    Primary source
    MGI:MGI:1914275
    See related
    Ensembl:ENSMUSG00000059291
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010203J19Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 384.9), liver E14 (RPKM 303.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rpl11 in Genome Data Viewer
    Location:
    4; 4 D3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (135776665..135780704, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (136049354..136053393, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (135605863..135609286, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene elongin A Neighboring gene uncharacterized LOC115489947 Neighboring gene predicted gene, 42329 Neighboring gene inhibitor of DNA binding 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 5S rRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables peroxisome proliferator activated receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin ligase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of protein neddylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of signal transduction by p53 class mediator IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization to nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein targeting ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in rRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of signal transduction by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal large subunit assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal large subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in polysomal ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025919.3NP_080195.1  60S ribosomal protein L11

      See identical proteins and their annotated locations for NP_080195.1

      Status: VALIDATED

      Source sequence(s)
      AK008422, BP770399, BX530725, CA321948
      Consensus CDS
      CCDS18799.1
      UniProtKB/Swiss-Prot
      Q9CXW4
      Related
      ENSMUSP00000099595.5, ENSMUST00000102536.11
      Conserved Domains (1) summary
      PTZ00156
      Location:5175
      PTZ00156; 60S ribosomal protein L11; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      135776665..135780704 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539112.3XP_006539175.1  60S ribosomal protein L11 isoform X1

      Related
      ENSMUSP00000121108.2, ENSMUST00000155873.3
      Conserved Domains (1) summary
      PTZ00156
      Location:8178
      PTZ00156; 60S ribosomal protein L11; Provisional
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