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    Med28 mediator complex subunit 28 [ Mus musculus (house mouse) ]

    Gene ID: 66999, updated on 23-Jun-2021

    Summary

    Official Symbol
    Med28provided by MGI
    Official Full Name
    mediator complex subunit 28provided by MGI
    Primary source
    MGI:MGI:1914249
    See related
    Ensembl:ENSMUSG00000015804
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Eg1; mag; FKSG20; magicin; AI451633; AU045690; 1500003D12Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 18.0), kidney adult (RPKM 11.1) and 28 other tissues See more
    Orthologs
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    Try the new Transcript table

    Genomic context

    See Med28 in Genome Data Viewer
    Location:
    5; 5 B3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (45677571..45686626)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (45520229..45529284)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (45911468..45920523)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene clarin 2 Neighboring gene leucine aminopeptidase 3 Neighboring gene family with sequence similarity 184, member B Neighboring gene RIKEN cDNA 9630001P10 gene Neighboring gene DDB1 and CUL4 associated factor 16 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (4)  1 citation
    • Chemically induced (ENU) (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cortical actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 28
    Names
    endothelial-derived
    mediator of RNA polymerase II transcription, subunit 28 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025895.4NP_080171.1  mediator of RNA polymerase II transcription subunit 28

      See identical proteins and their annotated locations for NP_080171.1

      Status: VALIDATED

      Source sequence(s)
      AC092711, DV653139
      Consensus CDS
      CCDS19275.1
      UniProtKB/Swiss-Prot
      Q920D3
      Related
      ENSMUSP00000115882.2, ENSMUST00000156481.8
      Conserved Domains (1) summary
      pfam11594
      Location:72166
      Med28; Mediator complex subunit 28

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      45677571..45686626
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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