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    Fip1l1 FIP1 like 1 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 66899, updated on 16-Oct-2021

    Summary

    Official Symbol
    Fip1l1provided by MGI
    Official Full Name
    FIP1 like 1 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1914149
    See related
    Ensembl:ENSMUSG00000029227
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rje; 1300019H17Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 15.0), CNS E14 (RPKM 12.7) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Fip1l1 in Genome Data Viewer
    Location:
    5; 5 C3.3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (74695774..74759451)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (74535438..74598790)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (74931507..74993149)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RAS-like, family 11, member B Neighboring gene Sec1 family domain containing 2 Neighboring gene predicted gene, 32064 Neighboring gene VISTA enhancer mm139 Neighboring gene ligand of numb-protein X 1 Neighboring gene predicted gene, 32304 Neighboring gene predicted gene 15984

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mRNA polyadenylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within mRNA polyadenylation IC
    Inferred by Curator
    more info
    PubMed 
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in pre-mRNA cleavage required for polyadenylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of mRNA cleavage and polyadenylation specificity factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mRNA cleavage and polyadenylation specificity factor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    pre-mRNA 3'-end-processing factor FIP1
    Names
    FIP1-like 1 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159573.2NP_001153045.1  pre-mRNA 3'-end-processing factor FIP1 isoform 1

      See identical proteins and their annotated locations for NP_001153045.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AC113300, AC164523
      Consensus CDS
      CCDS51520.1
      UniProtKB/Swiss-Prot
      Q9D824
      Related
      ENSMUSP00000109164.2, ENSMUST00000113536.8
      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    2. NM_001159574.2NP_001153046.1  pre-mRNA 3'-end-processing factor FIP1 isoform 3

      See identical proteins and their annotated locations for NP_001153046.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in the coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.
      Source sequence(s)
      AC113300, AC164523
      Consensus CDS
      CCDS51521.1
      UniProtKB/Swiss-Prot
      Q9D824
      Related
      ENSMUSP00000109163.3, ENSMUST00000113535.9
      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    3. NM_001376964.1NP_001363893.1  pre-mRNA 3'-end-processing factor FIP1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC113300, AC164523
      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    4. NM_001376965.1NP_001363894.1  pre-mRNA 3'-end-processing factor FIP1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC113300, AC164523
      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    5. NM_024183.6NP_077145.2  pre-mRNA 3'-end-processing factor FIP1 isoform 2

      See identical proteins and their annotated locations for NP_077145.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AC113300, AC164523
      Consensus CDS
      CCDS19346.1
      UniProtKB/Swiss-Prot
      Q9D824
      Related
      ENSMUSP00000079059.6, ENSMUST00000080164.12
      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      74695774..74759451
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504265.5XP_006504328.1  pre-mRNA 3'-end-processing factor FIP1 isoform X1

      See identical proteins and their annotated locations for XP_006504328.1

      Related
      ENSMUSP00000109162.3, ENSMUST00000113534.9
      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    2. XM_006504267.5XP_006504330.1  pre-mRNA 3'-end-processing factor FIP1 isoform X3

      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    3. XM_030254768.2XP_030110628.1  pre-mRNA 3'-end-processing factor FIP1 isoform X2

      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    4. XM_036165429.1XP_036021322.1  pre-mRNA 3'-end-processing factor FIP1 isoform X5

      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    5. XM_036165428.1XP_036021321.1  pre-mRNA 3'-end-processing factor FIP1 isoform X4

      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    6. XM_036165431.1XP_036021324.1  pre-mRNA 3'-end-processing factor FIP1 isoform X7

      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
    7. XM_036165430.1XP_036021323.1  pre-mRNA 3'-end-processing factor FIP1 isoform X6

      Conserved Domains (1) summary
      pfam05182
      Location:153195
      Fip1; Fip1 motif
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